Results 271 to 280 of about 303,496 (386)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Is Sex an Underrated Risk for Relapse in Substance Use Disorders? [PDF]

Brain Sci
Bohn A, Graf N, Scherbaum N, Deimel D, Schecke H.   +4 more
europepmc   +1 more source

Prescribing Psychostimulants for the Treatment of Stimulant Use Disorder: Navigating the Federal Legal Landscape

Leslie W. Suen, Phillip O. Coffin, Kathryn E. Boulton, Derek Carr, Corey S. Davis   +4 more
openalex   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Population-Level Trends in Attention-Deficit/Hyperactivity Disorder Medication Prescribing.

JAMA Netw Open
Myran DT, MacDonald-Spracklin R, Busa G, Talarico R, Finkelstein Y.   +4 more
europepmc   +1 more source

We Must Do Better on Implementing Evidence-Based Treatments for Substance Use Disorders. [PDF]

Am J Psychiatry
Higgins ST, Erath TG.
europepmc   +1 more source

Stimulant ADHD medication and risk for substance abuse.

Journal of Child Psychology and Psychiatry and Allied Disciplines, 2014
Z. Chang, P. Lichtenstein, L. Halldner, B. D’Onofrio, E. Serlachius, S. Fazel, Niklas Långström, H. Larsson   +7 more
semanticscholar   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

A randomised controlled trial to evaluate the clinical and cost-effectiveness of Stimulant compared with Non-stimulant medication for adults with Attention-deficit/hyperactivity disorder and a history of Psychosis or biPolar disordER: SNAPPER. [PDF]

Trials
Loi S, Joshee P, Ottridge R, Woolley R, Gkini E, Asherson P, Young AH, Al-Janabi H, Broome M, Roberts A, Gottlieb N, Hindmarch P, Silman D, Sharma P, Juruena M, Nair R, Mukherjee T, Katshu MZUH, Marwaha S.   +18 more
europepmc   +1 more source

VOMITING IN UTERINE HÆMORRHAGE.— STIMULANTS.

Archd. Blacklock
openalex   +2 more sources