Results 161 to 170 of about 263,271 (408)
Persian bee propolis and pollen extracts enhanced the non-specific immune response of rainbow trout (Onchorhynchus mykiss) and resistance against Aeromonas hydrophila [PDF]
, 2017 The effect of Persian bee propolis and pollen extracts on innate immune response of rainbow trout (Onchorhynchus mykiss) was investigated. Fish were fed diets containing 1% Pollen, 1% propolis and combination of the two immune-stimulants (0.5% Pollen and
Choobkar, N.
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Pulmonary artery smooth muscle cells response to vaso-active stimulations in a real-time 3-Dimensional model [PDF]
, 2006 INTRODUCTION: The tone of the pulmonary arteries is the summation of the activity of each smooth muscle cell (PASMC) within a vessel wall and its interaction with the endothelial cells and extracellular matrix (including collagen).
Hall, S, Mudera, V, Smith, T, Soueid, A
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Informational Requirements of A Mobile-Based System to Manage the Treatment of Stimulant Abusers
پیاورد سلامت, 2019 Background and Aim: Stimulants are among the most dangerous substances because of their physical and psychological side effects. The process of treating stimulant abusers is so complicated that makes the treatment very difficult.
Marjan Ghazi Saeedi +3 more
doaj
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source