Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Evaluation of Imoviral<sup>®</sup> effects on early immune response in <i>Sparus aurata</i> challenged with <i>Vibrio anguillarum</i>. [PDF]
Natale S +9 more
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Effect of the combination of Solanesol from <i>Nicotiana tabacum</i> with calcium hydroxide on tumor necrosis factor-alpha level in human dental pulp stem cells: An <i>in vitro</i> study. [PDF]
Widyastuti W +3 more
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Feasibility of Ti-6Al-4V Alloys with Nanoporous and Nanotubular Surfaces for the Treatment of Femoral Defects. [PDF]
Dos Santos DA +11 more
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
COVID-19 vaccine-induced autoimmune hyperthyroidism: Graves' disease. [PDF]
Murugan AK, Alzahrani AS.
europepmc +1 more source
Breastfeeding and interdental spacing in primary dentition: a digital cross-sectional study. [PDF]
Boo-Gordillo P +6 more
europepmc +1 more source
Feasibility and safety of 4DryField<sup>®</sup> PH as a hemostatic agent in ovarian surgery on fertility: a pilot randomized study. [PDF]
Tascón Padrón L +5 more
europepmc +1 more source

