Results 111 to 120 of about 976,503 (314)

Molecular design of light-responsive hydrogels, for in situ generation of fast and reversible valves for microfluidic applications [PDF]

, 2015
Reversible light-responsive hydrogel valves with response characteristics compatible for microfluidics have been obtained by optimization of molecular design of spiropyran photoswitches and gel composition.
Coleman, Simon, Stumpel, JE Jelle, Ben Azouz, A., Azouz, Aymen Ben, Jeroen ter Schiphorst (1535563), Albertus P. H. J. Schenning (1355601), Diamond, Dermot, Schiphorst, ter, J., Diamond, D, Dermot Diamond (1291743), Schenning, APHJ Albert, ter Schiphorst, Jeroen, Schenning, Albertus P.H.J., Simon Coleman (1535569), Schenning, A.P.H.J.; id_orcid, Aymen Ben Azouz (1535572), Schiphorst, J Jeroen ter, Stumpel, J.E., Diamond, D., Schenning, A.P.H.J., Stumpel, Jelle E., Jelle E. Stumpel (1535566), Coleman, S., Ben Azouz, Aymen   +23 more
core   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Biomedical applications of stimuli‐responsive nanomaterials

MedComm
Nanomaterials have aroused great interests in drug delivery due to their nanoscale structure, facile modifiability, and multifunctional physicochemical properties.
Xiaojie Chen, Di Wu, Zhong Chen
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Progress in Preparation and Application of Stimulus-response Zein-based Nanoparticles

Shipin gongye ke-ji
Zein is a primary by-product of corn starch processing, which is inexpensive and easily obtainable. Based on its unique self-assembly properties, zein could be constructed into nanoparticles through various methods, enabling the loading and delivery of ...
Wei WANG, Yan CUI, Mingzhu ZHENG, Meihong LIU, Huimin LIU   +4 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Photonic water dynamically responsive to external stimuli

Nature Communications, 2016
Some types of fish can change color by modifying their intracellular guanine crystal in response to external stimuli. Here, Sano et al. mimic this effect in a dilute aqueous dispersion containing titanate nanosheets, whose interlayer distance is tunable ...
Koki Sano, Youn Soo Kim, Yasuhiro Ishida, Yasuo Ebina, Takayoshi Sasaki, Takaaki Hikima, Takuzo Aida   +6 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source