Results 151 to 160 of about 1,377,636 (367)

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu   +10 more
wiley   +1 more source

Osteoclast‐Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes

open access: yesAdvanced Science, EarlyView.
In TMJ‐OA, osteoclasts play a significant role in promoting the growth of sensory nerves at the osteochondral interface. In early OA, TRAP+ osteoclast‐derived SLIT3 induces sensory nerve growth into the condylar cartilage. This nerve growth facilitates the development of pain associated with OA.
Weiwei Zhu   +13 more
wiley   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

open access: yesAdvanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang   +5 more
wiley   +1 more source

Timing precision of the Individual Differences in Dutch Language Skills (IDLaS-NL) test battery

open access: yesFrontiers in Human Neuroscience
Online experimentation has become an essential tool in cognitive psychology, offering access to diverse participant samples. However, remote testing introduces variability in stimulus presentation and response timing due to differences in participant ...
Janay Monen   +11 more
doaj   +1 more source

Decoding Proton‐Coupled Electron Transfer Mechanism of Nicotine for Multi‐Scenario Portable Electrochemical Sensing

open access: yesAdvanced Science, EarlyView.
A key challenge in nicotine electroanalysis is the unresolved complexity of its interface process, which directly determines sensor metrics. Herein, the proton‐coupled electron transfer mechanism of nicotine is decoded for multi‐scenario portable electrochemical sensing.
Yi Peng   +9 more
wiley   +1 more source

Skinner’s view on hallucinations. Validity and revision [PDF]

open access: yesPsychology, Society & Education, 2011
This work outlines the vision that B.F. Skinner held on hallucinations as psychological phenomena, and defends its validity and relevance nowadays. Our thesis starts with the Skinner’s conception on the behaviors of perceiving, imagining and dreaming. It
Marino Pérez Álvarez   +1 more
doaj  

Shedding Light on Common Misinterpretations in Photocatalyst Characterization

open access: yesAdvanced Energy Materials, EarlyView.
For heterogeneous semiconductor‐based photocatalysts, Marschall et al. highlight common misconceptions in material synthesis, characterization, and performance evaluation, together with detailed explanations on how to avoid them. The guidelines thus presented can help to improve reporting of photocatalyst performance in environmental applications, such
Roland Marschall   +2 more
wiley   +1 more source

Rethinking Power Solutions for Healthcare Wearables: From Point‐of‐Care and Episodic use to Continuous Monitoring and Therapeutic Platforms

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
This Perspective examines practical power solutions for wearable healthcare systems, highlighting the limits of standard batteries. It categorizes wearables into four domains—point‐of‐care diagnostics, episodic monitoring, continuous long‐term monitoring, and therapeutic platforms—and analyzes their power needs.
Seokheun Choi
wiley   +1 more source

The poetry of psychological distance: Bi-directional associations between stimulus speed and its psychological distance and construal level

open access: yesJournal of Personality and Social Psychology
Based on the cognitive ecological approach and on logical-functional principles, in twelve studies (eleven preregistered) we examine the novel hypotheses that psychological distance and construal level are associated in people’s minds with stimulus speed: the psychologically distant/abstract is slow, and the psychologically close/concrete is fast.
Ravit Nussinson   +8 more
openaire   +2 more sources

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