Results 51 to 60 of about 24,517 (327)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Basis for a theory of stipulation of wage
O presente estudo objetiva contribuir com a ciência jurídica na criação de bases para uma teoria de estipulação de salários. Existem algumas situações em que o pagamento apenas do salário base se mostra injusto e desigual, podendo mascarar grandes ...
Carvalho Filho, Renato Sabino
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Evaluating of Granting Conditional Agency in Divorce by Reviewing Judicial Decisions [PDF]
One of the functional divisions of contract and unilateral legal act is the division into definitive and conditional. Conditional contracts refer to contracts whose creation or effect is suspended by circumstances external to the contract. It is intended
seyedmohammaderfan farhani +1 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The Limits of Stipulation: Reconsidering the Standard Meter
This paper criticizes Ruffino’s illocutionary defense of Kripke’s famous example of the contingent a priori: the standard meter. Ruffino uses Searle and Vanderveken’s speech act theory to argue that measurement stipulations generate a priori knowledge ...
Eduardo Villanueva
doaj +1 more source
On Ritual Pollution by Seeing: I.Lindos II 487.1-3 and Hdt. 2.37.5
This paper focuses on the request not to look at breast-fed children attested at the beginning of the cathartic regulation from the sanctuary of Athena Lindia in Rhodes (I.Lindos II 487 = LSS 91).
Andrej Petrovic, Ivana Petrovic
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source

