Results 251 to 260 of about 9,502,067 (333)

Ancestral sequence reconstruction of the Mic60 Mitofilin domain reveals residues supporting respiration in yeast

Protein Science, Volume 34, Issue 7, July 2025.
Abstract In eukaryotes, cellular respiration takes place in the cristae of mitochondria. The mitochondrial inner membrane protein Mic60, a core component of the mitochondrial contact site and cristae organizing system, is crucial for the organization and stabilization of crista junctions and its associated functions.
Friederike M. C. Benning, Tristan A. Bell, Tran H. Nguyen, Della Syau, Louise B. Connell, Yi‐Ting Liao, Matthew P. Keating, Margaret Coughlin, Anja E. H. Nordstrom, Maria Ericsson, Corrie J. B. daCosta, Luke H. Chao   +11 more
wiley   +1 more source

Beyond high-level recommendations and rule books: doing the 'hard work' of global health research - lessons and recommendations from an interdisciplinary global partnership. [PDF]

BMJ Glob Health
Uny I, Kambalame L, Price H, Caes L, Kalumbi LR, Semple S, Lucas S, Orina F, Chasima T, Chamba MVM, Meme H.   +10 more
europepmc   +1 more source

A bio. tools collection of online resources for GPCR research

British Journal of Pharmacology, Volume 182, Issue 14, Page 3301-3319, July 2025.
G protein‐coupled receptors are highly complex signal transduction proteins with many potential biomedical applications. Researchers from different fields work together to improve mechanistic understanding of GPCR function and to transfer that knowledge in order to advance therapeutic options.
Tõnis Laasfeld, Friederike Wunsch, Avgi E. Apostolakou, Adrián García‐Recio, Gáspár Pándy‐Szekeres, Slawomir Filipek, Masha Y. Niv, Jana Selent, David E. Gloriam, Marcel Bermudez   +9 more
wiley   +1 more source

The implementation of safer drug consumption facilities in Scotland: a mixed methods needs assessment and feasibility study for the city of Edinburgh. [PDF]

Harm Reduct J
Nicholls J, Masterton W, Falzon D, McAuley A, Carver H, Skivington K, Dumbrell J, Perkins A, Steele S, Trayner K, Parkes T.   +10 more
europepmc   +1 more source

Multi‐Species Impacts of Invasive Opuntia Cacti on Mammal Habitat Use

Ecology Letters, Volume 28, Issue 7, July 2025.
Biological invasions impact ecosystems worldwide, including through changing the behaviour of native species. Here, we used camera traps to investigate the effects of invasive Opuntia spp. on the habitat use of 12 mammal species in an internationally important region of mammalian biodiversity.
Peter S. Stewart, Russell A. Hill, Ayub M. O. Oduor, Philip A. Stephens, Mark J. Whittingham, Wayne Dawson   +5 more
wiley   +1 more source

Recent evidence on rates and factors influencing smoking behaviours after release from smoke-free prisons: a scoping review. [PDF]

Int J Prison Health (2024)
Brown A, Woods-Brown C, Angus K, McMeekin N, Hunt K, Demou E.   +5 more
europepmc   +1 more source

Targeted protein degradation of PDE4 shortforms by a novel proteolysis targeting chimera

The FEBS Journal, Volume 292, Issue 13, Page 3360-3377, July 2025.
Here, we report KTX207, a previously undescribed cereblon‐based PDE4 PROTAC that can specifically target PDE4D shortform for degradation. We showed that KTX207 could improve selectivity, potency and enable a long‐lasting effect when used at a sub‐nanomolar concentration.
Yuan Yan Sin, Aoife Giblin, Aleksandra Judina, Punchita Rujirachaivej, Laura G. Corral, Eliza Glennon, Zhi Xian Tai, Tian Feng, Eduardo Torres, Alina Zorn, Julia Gorelik, Elka Kyurkchieva, Pa Thai Yenchitsomanus, Cathy Swindlehurst, Kyle Chan, David Stirling, George S. Baillie   +16 more
wiley   +1 more source

Inequalities of provision of nationally funded clinical academic training awards for healthcare professionals: quantitative comparisons across the four nations of the UK. [PDF]

J Res Nurs
Peters A, Cameron H, Cunningham S, Dawkes S, Donaldson J, Hughes L, Savinc J, MacArthur J.   +7 more
europepmc   +1 more source

“Don't Work for Soyciety:” Involuntary Celibacy and Unemployment

Gender, Work &Organization, Volume 32, Issue 4, Page 1556-1566, July 2025.
ABSTRACT Surveys of involuntary celibates (“incels”) suggest that they tend to be not in education, employment or training (NEET) at disproportionately high rates. However, it remains unclear whether and how being NEET is connected to incels' ideology and life circumstances.
AnnaRose Beckett‐Herbert, Eran Shor
wiley   +1 more source

Exploring barriers to the COVID-19 vaccine in people with psychoses in Western Australia. [PDF]

Prev Med Rep
Hall TM, Attwell K, Morgan VA, Hincks S, Waterreus A.   +4 more
europepmc   +1 more source