Results 241 to 250 of about 700,908 (311)

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Dynamic behavior of a stochastic epidemic model for skin sores: theoretical and computational perspectives. [PDF]

Sci Rep
Raza A, Lampart M, Rocha EM, Baleanu D, Taha HH, Fadhal E.   +5 more
europepmc   +1 more source

Stochastic inversion

SEG Technical Program Expanded Abstracts 1996, 1996
H. W. J. Debeye, E. Sabbah, P. M. van der Made   +2 more
openaire   +2 more sources

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Uncertainty-Aware Remaining Useful Life Prediction via Synergizing TCN-Transformer Networks and Fractional Brownian Motion. [PDF]

Entropy (Basel)
Geng Y, Yu T, Liu Y, Zhao J.
europepmc   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

A comment on: 'Development of Linear Interpolation System for SMK model parameters Evaluated from Cellular-scale simulation (LISMEC) and its application to BNCT dosimetry'. [PDF]

J Radiat Res
Mahida K, Jagtap SR.
europepmc   +1 more source

Metal‐Enhanced Charge Transport and its Mechanism in Atomically Precise Ruthenium Single‐Molecule Devices

Advanced Science, EarlyView.
An atomically precise platform was developed for investigating single‐molecule charge transport. This innovative platform enables the creation of highly uniform molecular devices using ruthenium‐based molecules. It reveals a significant enhancement in molecular conductance due to the metallic ruthenium center and a unique barrier‐lowering effect during
Jie Guo, Qinghua Gao, Ping Duan, Cong Zhao, Huimin Wen, Xiaoyan He, Lucie Norel, Yuzhe Zhang, Chunwen Wang, Wu Zhou, Xinyue Chang, Ju Wang, Stéphane Rigaut, Mingliang Li, Chuancheng Jia, Xuefeng Guo   +15 more
wiley   +1 more source

Treeline Provides a Unified Strategy for Optimising Phylogenetic Trees Under Alternative Criteria. [PDF]

Mol Ecol Resour
Wright ES.
europepmc   +1 more source

Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR‐NK Therapeutic Strategies

Advanced Science, EarlyView.
This study presents a 3D embedded bioprinting platform that recapitulates key stromal features of the tumor microenvironment using fibroblasts and lung‐derived ECM. The model enables functional assessment of CAR‐NK cells and provides a versatile tool to support the development of next‐generation immunotherapeutic strategies against solid tumors ...
Dahong Kim, Seona Jo, In‐Hwan Jang, Yu‐Jin Kim, Youngmee Jung, Junhyoung Ahn, Hyungjun Lim, Jae Jong Lee, Kangwon Lee, Tae‐Don Kim, Su A Park   +10 more
wiley   +1 more source