Results 241 to 250 of about 78,218 (312)

Predicting Cardiovascular Events with Time-Lagged Inflammatory Dynamics: Stochastic Delay Modeling. [PDF]

Comput Struct Biotechnol J
Vallée A.
europepmc   +1 more source

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

Advanced Science, EarlyView.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang, Xiaoqing Gong, Shukai Gu, Jing Li, Bo Liu, Yanan Tian, Qianqian Zhang, Xiaojun Yao, Huanxiang Liu   +8 more
wiley   +1 more source

The Role of Viral Dynamics and Infectivity in Models of Oncolytic Virotherapy for Tumours with Different Motility. [PDF]

Bull Math Biol
Morselli D, Frascoli F, Delitala ME.
europepmc   +1 more source

Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks

Advanced Science, EarlyView.
Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley   +1 more source

From Label‐Free Multiphoton Imaging to Pathological Reports: A Vision‐Language Breast Cancer Margin Pathological Diagnosis System

Advanced Science, EarlyView.
MarginPath is a novel vision‐language system that automates breast cancer margin assessment using a single label‐free multiphoton microscopy image. By integrating tumor‐associated collagen signatures with virtual H&E imaging, it generates accurate margin heatmaps and comprehensive diagnostic reports.
Shu Wang, Jingze Su, Xiahui Han, Deyong Kang, Xiao Zhang, Fei Xu, Changzu Liu, Junlin Pan, Xingfu Wang, Qiaohui Zhan, Aimin Wang, Feng Huang, Heping Cheng, Wenxi Liu, Ruolan Lin, Jianxin Chen   +15 more
wiley   +1 more source

Optimization of urban freight intelligent route based on reinforcement learning. [PDF]

Sci Rep
Xin G, Tang Y, Gao H, Li N.
europepmc   +1 more source

An improved sinh cosh optimizer for optimal scheduling of a microgrid with multi-energy resources and storage considering different weather conditions. [PDF]

Sci Rep
Ma J, Shen H, Nowdeh SA.
europepmc   +1 more source

Dynamic properties of an SARS-CoV-2 epidemic model via stochastic PINNs. [PDF]

Infect Dis Model
Xie L, Yang J, Li Z.
europepmc   +1 more source

Marketing of Slow-Track Rather than Fast-Track Animals Reduces Mean Length of Stay and Animal Shelter Census Count: A Theoretical Study. [PDF]

Animals (Basel)
Mavrovouniotis ML.
europepmc   +1 more source

Resilience-oriented optimization of hospital microgrids with critical load support using ESS and PV under grid outage conditions. [PDF]

Sci Rep
Nazartalab P, Alavi-Rad H.
europepmc   +1 more source