Results 231 to 240 of about 30,075 (285)

Inference of ecological networks and possibilistic dynamics based on Boolean networks from observations and prior knowledge

Methods in Ecology and Evolution, EarlyView.
Abstract Being able to infer the interactions between a set of species from observations of the system is of paramount importance to obtain explanatory and predictive models in ecology. We tackled this challenge by employing qualitative modelling frameworks and logic methods for the synthesis of mathematical models that can integrate both observations ...
Loïc Paulevé, Cédric Gaucherel
wiley   +1 more source

Evolutionary Implications of Self-Assembling Cybernetic Materials with Collective Problem-Solving Intelligence at Multiple Scales. [PDF]

Entropy (Basel)
Hartl B, Risi S, Levin M.
europepmc   +1 more source

Multi‐Omics Analysis Reveals Biomarkers That Contribute to Biological Age Rejuvenation in Response to Single‐Blinded Randomized Placebo‐Controlled Therapeutic Plasma Exchange

Aging Cell, EarlyView.
Therapeutic plasma exchange safely reduces biological age by up to 2.6 years. Multi‐omics analysis reveals coordinated cellular and molecular responses associated with aging rejuvenation. ABSTRACT We conducted a randomized, placebo‐controlled trial to assess the safety and biological age (BA) effects of various therapeutic plasma exchange (TPE ...
Matias Fuentealba, Dobri Kiprov, Kevin Schneider, Wei‐Chieh Mu, Prasanna Ashok Kumaar, Herbert Kasler, Jordan B. Burton, Mark Watson, Heather Halaweh, Christina D. King, Zehra Stara Yüksel, Chelo Roska‐Pamaong, Birgit Schilling, Eric Verdin, David Furman   +14 more
wiley   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source

Spatial organization and stochastic fluctuations of immune cells impact clinical responsiveness to immunotherapy in melanoma patients. [PDF]

PNAS Nexus
Giuliani G, Stewart W, Li Z, Jayaprakash C, Das J.   +4 more
europepmc   +1 more source

Deep learning model for detecting cystoid fluid collections on optical coherence tomography in X‐linked retinoschisis patients

Acta Ophthalmologica, EarlyView.
Abstract Purpose To validate a deep learning (DL) framework for detecting and quantifying cystoid fluid collections (CFC) on spectral‐domain optical coherence tomography (SD‐OCT) in X‐linked retinoschisis (XLRS) patients. Methods A no‐new‐U‐Net model was trained using 112 OCT volumes from the RETOUCH challenge (70 for training and 42 for internal ...
Jonathan Hensman, Yasmine el Allali, Hind Almushattat, Coen de Vente, Clara I. Sánchez, Camiel J. F. Boon   +5 more
wiley   +1 more source

Validation of target‐enriched enzymatic methylation sequencing for brain tumor classification from formalin‐fixed paraffin embedded‐derived DNA

Brain Pathology, EarlyView.
Target‐enriched enzymatic methylation sequencing (TEEM‐seq), a DNA methylation sequencing method using the Twist Human Methylome panel, shows comparable performance to array‐based tumor methylation profiling. The method is compatible with both frozen and formalin‐fixed paraffin‐embedded (FFPE) samples and is a viable approach to tumor methylation and ...
Quynh T. Tran, Sujuan Jia, Md. Zahangir Alom, Lu Wang, Charles G. Mullighan, Ruth G. Tatevossian, Brent A. Orr   +6 more
wiley   +1 more source

Information transmission in a cell monolayer: A numerical study. [PDF]

PLoS Comput Biol
Nałęcz-Jawecki P, Szyc P, Grabowski F, Kochańczyk M, Lipniacki T.   +4 more
europepmc   +1 more source

ABSTRACTS

Precision Radiation Oncology, EarlyView.
wiley   +1 more source

Stereological analysis of cholinergic neurons within bilateral pedunculopontine nuclei in health and when affected by Parkinson's disease

Brain Pathology, EarlyView.
(A) PPN‐cholinergic neurons degenerate during PD. We stereologically counted their rostro‐caudal distribution in post‐mortem PPNs in health versus PD. (Bi) Serial PPN‐containing samples were cholinergic antibody‐DAB stained. (Bii) Only DAB‐stained neurons on green lines and inside the box were counted.
Puneet Kumar Sharma, Steve Gentleman, David Trevor Dexter, Ilse Sanet Pienaar   +3 more
wiley   +1 more source