Results 51 to 60 of about 167,189 (264)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Stochastic Energy Management Strategy for Autonomous PV–Microgrid Under Unpredictable Load Consumption

open access: yesIEEE Access
This paper introduces a novel energy management strategy incorporating stochastic elements designed for off-grid photovoltaic (PV) systems supplying multiple loads in environments marked by unpredictable power usage.
Mohamed Aatabe   +5 more
doaj   +1 more source

Company Value with Ruin Constraint in a Discrete Model

open access: yesRisks, 2018
Optimal dividend payment under a ruin constraint is a two objective control problem which—in simple models—can be solved numerically by three essentially different methods.
Christian Hipp
doaj   +1 more source

On the Solutions of a Stochastic Control System [PDF]

open access: yesSIAM Journal on Control, 1971
The control system considered in this paper is modeled by the stochastic differential equation \[dx(t,\omega ) = f(t,x( \cdot ,\omega ),u(t,\omega ))dt + dB(t,\omega ),\] where B is n-dimensional Brownian motion, and the control u is a nonanticipative functional of $x( \cdot ,\omega )$ taking its values in a fixed set U.
Duncan, Tyrone E., Varaiya, Pravin
openaire   +3 more sources

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

NeuRehab: a reinforcement learning and spiking neural network-based rehab automation framework

open access: yesNeuromorphic Computing and Engineering
Recent advancements in robotic rehabilitation therapy have provided modular exercise systems for post-stroke muscle recovery with basic control schemes. But these systems struggle to adapt to patients’ complex and ever-changing behaviour, and to operate ...
Phani Pavan Kambhampati   +3 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Controlled Filtered Poisson Processes

open access: yesMathematics
Filtered Poisson processes are used as models in various applications, in particular in statistical hydrology. In this paper, controlled filtered Poisson processes are considered.
Mario Lefebvre
doaj   +1 more source

Reaction-diffusion systems in natural sciences and new technology transfer

open access: yesJournal of the Mechanical Behavior of Materials, 2012
Diffusion mechanisms in natural sciences and innovation management involve partial differential equations (PDEs). This is due to their spatio-temporal dimensions.
Keller André A.
doaj   +1 more source

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