Results 201 to 210 of about 836,551 (359)
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang+14 more
wiley +1 more source
Numerical Methods in the Weak Sense for Stochastic Differential Equations with Small Noise [PDF]
Grigori N. Milstein, M. V. Tretyakov
openalex +1 more source
EGR1 Promotes Craniofacial Bone Regeneration via Activation of ALPL⁺PDGFD⁺ Periosteal Stem Cells
ALPL+PDGFD+ (AP+) cells are distinct calvarial periosteal stem cells (PeSCs) with diminished postnatal activity. EGR1 drives PeSCs development via BMP signaling through its Znf2 domain and activates them via CTNNB1/WNT10B signaling through its Znf2/3 domains.
Yang Li+15 more
wiley +1 more source
Approximation of stochastic differential equations driven by α-stable Lévy motion [PDF]
Aleksander Janicki+2 more
openalex +1 more source
Network Desynchronization with Sine Waves: from Synchrony to Asynchrony by Periodic Stimulation
Exogenous alternating current fields are explored and interact with cerebral cortex slow waves in vitro and in silico. Varying frequency and amplitude of sine waves result in distinct network dynamics, from phase‐locking and entrainment to desynchronization. These responses occupy specific regions within the parameter space.
Joana Covelo+4 more
wiley +1 more source
Wick product and stochastic partial differential equations with Poisson measure [PDF]
Azzouz Dermoune
openalex +1 more source
Biosecurity Primitive: Polymerase X‐based Genetic Physical Unclonable Functions
What if every cell line can carry an unforgeable genomic fingerprint—one that proves its origin, ensures its authenticity, and thwarts unauthorized duplication? Here, CRISPR‐induced DNA lesions paired with TdT‐mediated repair produce robust, unique, and unclonable genetic signatures—advancing the concept of molecular Physical Unclonable Functions (PUF)
Zikun Zhou+7 more
wiley +1 more source
This research presents a novel optimization method for the inverse design of flexible mechanical metamaterials, enhancing traditional strategies by evaluating deformation in subregions. Combining simulated annealing with a genetic algorithm, it improves design efficiency and enables customizable deformation paths.
Xueqing Cao+4 more
wiley +1 more source
Stochastic Partial Differential Equations: A Modeling, White Noise Functional Approach. [PDF]
Alfred Schöttl+4 more
openalex +1 more source
This study integrates dual‐reporter genetics, imaging flow cytometry, and single‐cell sequencing to characterize rare bihormonal cells in mouse and human pancreatic islets. Gcg⁺Ins⁺ cells resemble α‐cells rather than transitional states. Cross‐species gene network analysis refines islet cell taxonomy and reveals human‐specific δ‐cell subtypes ...
Xin‐Xin Yu+10 more
wiley +1 more source