Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu +14 more
wiley +1 more source
Intelligent regulation of university faculty interdisciplinary collaboration networks based on complex network topology evolution and stochastic differential equations. [PDF]
Ren S.
europepmc +1 more source
Nanoscale Mapping of the Subcellular Glycosylation Landscape
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter +4 more
wiley +1 more source
Asymptotic expansions as control variates for deep solvers to fully-coupled forward-backward stochastic differential equations. [PDF]
Naito M +3 more
europepmc +1 more source
The Asymptotic Behavior for Second‐Order Neutral Stochastic Partial Differential Equations with Infinite Delay [PDF]
Huabin Chen
openalex +1 more source
Reliable AI Platform for Monitoring BCI Caused Brain Injury and Providing Real‐Time Protection
BrainGuard enables real‐time and interpretable assessment of brain injury caused by brain computer interface (BCI). Using feature‐based Gaussian process (GP) emulators trained on limited biomechanical data, it efficiently predicts full‐field strain and constructs patient‐specific digital brain twins to support clinical diagnosis and long‐term BCI ...
Chufan He +3 more
wiley +1 more source
Convergence of Relative Entropy for Euler-Maruyama Scheme to Stochastic Differential Equations with Additive Noise. [PDF]
Yu Y.
europepmc +1 more source
Strong Proton‐Phonon Coupling Drives Fast Ion Transport in Perovskites
Experimental and computational phonon analysis of ABO3‐type proton conductor BaSnO3 shows that substitution on the B‐site with yttrium forms an imaginary phonon mode which is instrumental for the function as proton conductor. This overcompensates the adverse proton trapping effect of the yttrium.
Alexey Rulev +8 more
wiley +1 more source
Modeling single cell trajectory using forward-backward stochastic differential equations. [PDF]
Zhang K, Zhu J, Kong D, Zhang Z.
europepmc +1 more source
Existence and uniqueness of the solution of a stochastic differential equation, driven by fractional Brownian motion with a stabilizing term [PDF]
Yuliya Mishura, S. V. Posashkov
openalex +1 more source

