Results 251 to 260 of about 280,972 (398)

Artificial intelligence streamlines scientific discovery of drug–target interactions

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Drug discovery is a complicated process through which new therapeutics are identified to prevent and treat specific diseases. Identification of drug–target interactions (DTIs) stands as a pivotal aspect within the realm of drug discovery and development. The traditional process of drug discovery, especially identification of DTIs, is marked by
Yuxin Yang, Feixiong Cheng
wiley   +1 more source

Unlocking university efficiency: a Bayesian stochastic frontier analysis [PDF]

open access: hybrid
Zaira García‐Tórtola   +3 more
openalex   +1 more source

Environmentally adjusted productivity growth and shadow prices for dairy farms

open access: yesCanadian Journal of Agricultural Economics/Revue canadienne d'agroeconomie, EarlyView.
Abstract We estimate the environmentally adjusted productivity growth and shadow price for Ontario dairy farms. We use an input‐oriented directional distance function and farm‐level data from 2000 to 2020. First, we find that while GHG emissions per cow increase with higher milk yields, emission intensity decreases as milk yield per cow increases.
Bibek Dahal   +2 more
wiley   +1 more source

Block scheduling in practice: An optimal decomposition strategy for nonidentical operating rooms

open access: yesDecision Sciences, EarlyView.
Abstract We develop and implement a Master Surgery Schedule for a real‐life hospital, assigning operating room (OR) time to surgical specialties over a multi‐week horizon. Through action research, we identify a critical operational challenge: the issue of split blocks. Split blocks allow two specialties to share an OR on the same day—one in the morning,
Vincent J. J. van Ham   +2 more
wiley   +1 more source

Risk stratification using coronary artery calcium and potential benefit of semaglutide therapy: A cost‐effectiveness modelling study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aim Coronary artery calcium (CAC) scoring is observed to improve risk stratification for major adverse cardiovascular events (MACE). Semaglutide, a recently introduced anti‐obesity drug, is very effective, but wider use is limited due to high costs.
Sai Rahul Ponnana   +11 more
wiley   +1 more source

The Impact of Risk Exposure and Environmental Conditions on European Banking Efficiency

open access: yesEuropean Financial Management, EarlyView.
ABSTRACT This study investigates the determinants of bank cost efficiency in Europe by applying a dynamic Bayesian stochastic frontier approach. We distinguish between two conceptually and empirically separate components of efficiency: (1) an intrinsic component, driven by internal bank features such as size and risk exposure, and (2) an extrThis study
Pilar Gargallo   +2 more
wiley   +1 more source

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