Results 281 to 290 of about 61,950 (353)

Redox environment modulates aggregation of ataxin‐3 in vitro — Implications for drug screening of cysteine‐rich proteins

open access: yesThe FEBS Journal, EarlyView.
Redox environment modulates in vitro aggregation of Ataxin‐3, the protein implicated in spinocerebellar ataxia type 3. Reducing conditions stabilize native monomers and prevent aggregation, whereas oxidative conditions promote the formation of non‐native conformers and disulfide‐linked oligomers within the Josephin domain (JD).
Martyna Podlasiak   +10 more
wiley   +1 more source

Geopolitical Risk and Domestic Bank Deposits

open access: yesFinancial Management, EarlyView.
ABSTRACT We investigate the relationship between global geopolitical risk and bank deposit flows across a wide panel of European countries. Motivated by the pivotal role of deposit stability for financial intermediation and systemic resilience, we explore whether geopolitical shocks alter depositors’ portfolio choices.
Dimitris Anastasiou   +3 more
wiley   +1 more source

How to improve the construction efficiency of key medical disciplines: a three-stage DEA. [PDF]

open access: yesCost Eff Resour Alloc
Sun H   +6 more
europepmc   +1 more source

Testing for Contagion in International Financial Markets: To See More, Go Higher

open access: yesFinancial Review, EarlyView.
ABSTRACT Traditional measures of financial contagion rely on correlation shifts, overlooking higher moments such as skewness and kurtosis. We examine contagion during two major financial crises, incorporating lower‐ and higher‐moment measures. We analyze stock market returns from 22 major markets at different frequencies, offering a global perspective ...
Simeon Coleman, Vitor Leone
wiley   +1 more source

Simulation-Based Optimization over Discrete Spaces Using Projection to Continuous Latent Spaces. [PDF]

open access: yesInd Eng Chem Res
Hernández-Morales G   +3 more
europepmc   +1 more source

Multi‐Objective Optimization of a Hydro‐Economic Model in an Over‐Allocated Agricultural Basin

open access: yesGroundwater, EarlyView.
Abstract Groundwater depletion for agricultural irrigation poses significant environmental and economic challenges. This study introduces a proof‐of‐concept that combines hydro‐economic modeling, scenario‐based modeling, and multi‐objective optimization to manage pumping curtailment in an over‐allocated basin in the western United States.
Katherine H. Markovich   +5 more
wiley   +1 more source

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