Results 181 to 190 of about 23,797 (211)

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

Entropy Regularization in Deep Reinforcement Learning: A Structured Review Across Classical Control, Generative Policies, and Reasoning Language Models. [PDF]

Entropy (Basel)
Taricco G.
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

A genetic algorithm for self-supervised models of oscillatory neurodynamics. [PDF]

PLoS One
Nejat H, Sherfey J, Bastos AM.
europepmc   +1 more source

From Magnetic Fibers to Paper Architectures: A Lightweight Strategy for Robust Low‐Frequency Microwave Absorption

Advanced Science, EarlyView.
A scalable process converts para‐aramid fibers into soft‐magnetic building blocks via micrometer‐thick Fe0.64Ni0.36 (Invar‐type) coatings. Assembled into paper, they form a hierarchical conductive network whose tunable permeability enables thin, lightweight microwave absorption in the low‐frequency (S‐band) regime.
You Wu, Yanlong Li, Haitong Sun, Tao Liu, Kehai Liu, Kaihui Liu, Zhaoxia Sun, Wenbo Ju   +7 more
wiley   +1 more source

Hybrid Quantum-Classical Algorithm for Robust Optimization via Stochastic-Gradient Online Learning. [PDF]

Quantum Mach Intell
Lim D, Doriguello JF, Rebentrost P.
europepmc   +1 more source

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

Advanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer, Rong Zhu, Manuel Reithofer, Gerhard Stadlmayr, Katharina Stadlbauer, Panchika Prangkio, Christoph Rippel, Markus Hahn, Aniko Eva Kasztner, Stefanie Stohl, Petr Bednar, Daniel Ruzek, David Glück, Robert Tampé, Gordana Wozniak‐Knopp, Yoo Jin Oh, Miriam Klausberger, Peter Hinterdorfer   +17 more
wiley   +1 more source

Exact Discrete Stochastic Simulation With Deep-Learning-Scale Gradient Optimization. [PDF]

Adv Sci (Weinh)
Vilar JMG, Saiz L.
europepmc   +1 more source

Mesoporous‐Shell Monolayer Plasmonic Architecture Enables Quantitative and Decision‐Guided SERS

Advanced Science, EarlyView.
Mesoporous‐shell‐regulated molecular transport combined with monolayer hotspot determinism transforms surface‐enhanced Raman spectroscopy (SERS) from ultrasensitive detection into quantitative and decision‐guided molecular sensing. ABSTRACT Quantitative surface‐enhanced Raman spectroscopy (SERS) has long been impeded by stochastic hotspot formation ...
Guangyao Huang, Ying Wang, Yue Fang, Jingyuan Shao, Sensen Hao, Mancun Zhao, Yuan Yao, Junping Wang, Wei Zhou, Hongzhi Wang   +9 more
wiley   +1 more source

NOISY MRI RECONSTRUCTION VIA MAP ESTIMATION WITH AN IMPLICIT DEEP-DENOISER PRIOR. [PDF]

Proc Int Conf Image Proc
Janjušević N, Khalilian-Gourtani A, Wang Y, Feng L.   +3 more
europepmc   +1 more source