Cancer‐Like Fragmentomic Characteristics of Somatic Variants in Cell‐Free DNA
Advanced Science, EarlyView.We report that in non‐cancerous subjects, cell‐free (cfDNA) molecules harboring somatic variants exhibit cancer‐like fragmentomic characteristics associated with clonal hematopoiesis. Importantly, these somatic variant‐associated fragmentomic aberrations are more pronounced in cancer patients. Leveraging such somatic variant‐associated signals in cfDNA,
Zhenyu Zhang +12 more
wiley +1 more source
On the Change of Measure for Brownian Processes. [PDF]
Entropy (Basel)Pinski FJ.
europepmc +1 more source
Real‐Time In Vivo Cellular‐Level Imaging During Puncture
Advanced Science, EarlyView.We present an artificial‐intelligence‐empowered integrative‐light‐field microendoscopy (AIM) needle that delivers real‐time in vivo, diffraction‐limited cellular‐level imaging during puncture and visualizes layered microstructures along the needle path. As a microscopic complement to CT/ultrasound, it improves sampling localization and adds preliminary
Huifang Gao +13 more
wiley +1 more source
Collectively-Modified Intermolecular Electron Correlations: The Connection of Polaritonic Chemistry and Spin Glass Physics. [PDF]
Chem RevSidler D, Ruggenthaler M, Rubio A.
europepmc +1 more source
Advanced Science, EarlyView.A spectrally and kinetically multiplexed single‐molecule imaging method is developed, which achieved simultaneous imaging of 12 exosomal proteins at an unparalleled single‐copy resolution. It is found that co‐occurrence of α6 integrin and the pairing β counterpart on single exosomes is essential for lung targeting, providing valuable information for ...
Songlin Liu +10 more
wiley +1 more source
Nonstationary Stochastic Responses of Transmission Tower-Line System with Viscoelastic Material Dampers Under Seismic Excitations. [PDF]
Materials (Basel)Chang M, Chen B, Xiao X, Chen Y.
europepmc +1 more source
Advanced Science, EarlyView.General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen +11 more
wiley +1 more source
Entropy-Based Evidence Functions for Testing Dilation Order via Cumulative Entropies. [PDF]
Entropy (Basel)Alshehri MA.
europepmc +1 more source
A Quasi-Monte Carlo Method Based on Neural Autoregressive Flow. [PDF]
Entropy (Basel)Wei Y, Xi W.
europepmc +1 more source
The Statistical Thermodynamics of Generative Diffusion Models: Phase Transitions, Symmetry Breaking, and Critical Instability. [PDF]
Entropy (Basel)Ambrogioni L.
europepmc +1 more source