FAK signaling drives chemoresistance and tumor evolution in pancreatic ductal adenocarcinoma. The FAK inhibitor IN10018 restores gemcitabine sensitivity by inducing SLC7A11‐mediated ferroptosis through the PI3K‐Akt pathway and remodeling the tumor microenvironment, reducing mesenchymal components while enhancing CD8+ T‐cell infiltration in preclinical ...
Yingjin Wang +11 more
wiley +1 more source
HySimODE: a hybrid stochastic-deterministic simulation framework for multiscale models of biological systems. [PDF]
Zamora-Chimal CG, Darlington APS.
europepmc +1 more source
Defect‐Functionalization‐Mediated Tunneling Drives Nonlinear Photoemission in Perovskites
This cover illustration depicts CsPbBr3 perovskite nanocrystals embedded with functionalized defect vacancies, where electrons migrate through defect‐mediated pathways and emit as lightning‐like beams. The imagery visualizes the core discovery of our work—defect‐functionalization‐mediated tunneling enabling nonlinear photoemission, where deep‐level ...
Hang Ren +9 more
wiley +1 more source
Stochastic optimization framework for microgrid energy management integrating electric vehicles, renewable sources, and storage. [PDF]
Ali ZM, Mostafa MH.
europepmc +1 more source
A physics‐based framework resolving graphite phase‐separation dynamics establishes a predictive, degradation‐aware fast‐charging methodology for commercial Li‐ion batteries. The resulting model‐informed protocol achieves 20%–80% state‐of‐charge in 14 min while matching the long‐term degradation of a commercial 25‐minute EV strategy.
Marco Lagnoni +10 more
wiley +1 more source
Effective elastic properties and conductivity of minimal surface based stochastic and periodic metamaterials. [PDF]
Abubaker HM +3 more
europepmc +1 more source
Stochastic Poisson-embedded privacy framework for federated learning with secure homomorphic encryption in medical AI. [PDF]
Gomathi R +3 more
europepmc +1 more source
An improved sinh cosh optimizer for optimal scheduling of a microgrid with multi-energy resources and storage considering different weather conditions. [PDF]
Ma J, Shen H, Nowdeh SA.
europepmc +1 more source
Discrete stochastic maximal regularity. [PDF]
Evangelopoulos-Ntemiris F, Veraar M.
europepmc +1 more source
Dynamic properties of an SARS-CoV-2 epidemic model via stochastic PINNs. [PDF]
Xie L, Yang J, Li Z.
europepmc +1 more source

