Results 131 to 140 of about 235,966 (268)

A mixed-effects stochastic model reveals clonal dominance in gene therapy safety studies. [PDF]

open access: yesBMC Bioinformatics, 2023
Del Core L   +3 more
europepmc   +1 more source

From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates

open access: yesAdvanced Materials, EarlyView.
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot   +3 more
wiley   +1 more source

Noise‐Tunable Memristor Enabling Programmable Probabilistic Neurons for Frequency‐Selective Time‐Series Signal Encoding

open access: yesAdvanced Materials, EarlyView.
Memristors offer tunable resistance and intrinsic instability, making them promising tunable noise sources. We propose a spiking‐rate‐programmable probabilistic neuron using a Ru/TaOx/Pt memristor, where resistance‐dependent noise enables frequency‐selective encoding.
Do Hoon Kim   +8 more
wiley   +1 more source

Stochastic model of IP3-induced Ca2+ spiking of HEK293 cells. [PDF]

open access: yesPLoS Comput Biol
Azzoni C   +5 more
europepmc   +1 more source

Flax Composites With Improved Interfacial Strength Through Microbially Induced Mineral Precipitation

open access: yesAdvanced Materials, EarlyView.
A bio‐inspired biomineralization strategy introduces an additional hierarchy to flax fiber composites. By controlling microbe‐mediated mineral particle deposition through tuned salt concentrations, stress transfer within the natural fiber composite is enhanced.
Deniz Sayinbas   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy