Advanced Science, EarlyView.scPER presents an adversarial‐autoencoder framework that deconvolves bulk total RNA‐seq to quantify tumor‐microenvironment cell types and uncover phenotype‐linked subclusters. Across diverse benchmarks, scPER improves accuracy over existing tools.
Bingrui Li, Xiaobo Zhou, Raghu Kalluri
wiley +1 more source
Neural variability in the medial prefrontal cortex contributes to efficient adaptive behavior. [PDF]
Nat CommunFindling C +3 more
europepmc +1 more source
Principles for Rigorous Design and Application of Synthetic Microbial Communities
Advanced Science, EarlyView.SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang +21 more
wiley +1 more source
An improved weighted average algorithm with Cloud-Based Risk-Conscious stochastic model for building energy optimization. [PDF]
Sci RepKeawsawasvong S +2 more
europepmc +1 more source
Active Force Dynamics in Red Blood Cells Under Non‐Invasive Optical Tweezers
Advanced Science, EarlyView.A non‐invasive method combines low‐power optical tweezers with high‐speed microscopy to simultaneously monitor local membrane forces and displacements in single human red blood cells. This dual‐channel approach reveals a mechano‐dynamic signature that correlates the cell's metabolic state with its mechanical activity. This energetic framework serves as
Arnau Dorn +5 more
wiley +1 more source
Real‐Time In Vivo Cellular‐Level Imaging During Puncture
Advanced Science, EarlyView.We present an artificial‐intelligence‐empowered integrative‐light‐field microendoscopy (AIM) needle that delivers real‐time in vivo, diffraction‐limited cellular‐level imaging during puncture and visualizes layered microstructures along the needle path. As a microscopic complement to CT/ultrasound, it improves sampling localization and adds preliminary
Huifang Gao +13 more
wiley +1 more source
Quantifying and comparing causal patterns in stochastic chemical reaction networks. [PDF]
NPJ Syst Biol ApplKahramanoğulları O.
europepmc +1 more source
An assessment of first-order stochastic dispersion theories in porous media
, 1997 David A. Chin
openalex +1 more source
AI‐Directed 3D Printing of Hierarchical Polyurethane Foams
Advanced Science, EarlyView.Digitally guided direct ink writing, combined with AI‐generated design, enables the fabrication of hierarchical polyurethane foams with tunable multiscale porosity. This approach produces architected foams featuring interconnected open‐cell networks and tailored mechanical properties, advancing the development of adaptive, high‐performance materials ...
Dhanush Patil +15 more
wiley +1 more source
Numerical Integration of Stochastic Differential Equations: The Heun Algorithm Revisited and the Itô-Stratonovich Calculus. [PDF]
Entropy (Basel)Mannella R.
europepmc +1 more source