Results 181 to 190 of about 661,238 (311)

CPL‐Diff: A Diffusion Model for De Novo Design of Functional Peptide Sequences with Fixed Length

open access: yesAdvanced Science, EarlyView.
This study presents a diffusion model for generating functional peptide sequence lengths using mask control. The model can generate antimicrobial, antifungal, and antiviral peptides with specific lengths on demand. The model learns the structure of peptides better and generates peptides with better physicochemical properties, and the model has good ...
Zhenjie Luo   +5 more
wiley   +1 more source

Optimal control for stochastic neural oscillators. [PDF]

open access: yesBiol Cybern
Rajabi F, Gibou F, Moehlis J.
europepmc   +1 more source

A Multi‐Task Self‐Supervised Strategy for Predicting Molecular Properties and FGFR1 Inhibitors

open access: yesAdvanced Science, Volume 12, Issue 13, April 3, 2025.
The overview of MTSSMol during pretraining. Initially, data augmentation techniques are applied to the raw input data to create various enhanced versions. These images are then fed into GNNs to extract latent features. Finally, the augmented data is utilized for two learning tasks. b.
Xin Yang   +6 more
wiley   +1 more source

Exploring the Latent Information in Spatial Transcriptomics Data via Multi‐View Graph Convolutional Network Based on Implicit Contrastive Learning

open access: yesAdvanced Science, EarlyView.
STMIGCL is an implicit contrastive learning‐based multi‐view graph convolutional network framework designed for downstream tasks such as spatial domain recognition, trajectory inference, and spatially variable gene identification. By combining multi‐view learning with contrastive learning and employing contrastive learning methods that enhance contrast
Sheng Ren   +5 more
wiley   +1 more source

The FitzHugh-Nagumo equations and quantum noise. [PDF]

open access: yesComput Struct Biotechnol J
Ghose P, Pinotsis DA.
europepmc   +1 more source

Pupylation‐Based Proximity Labeling Unravels a Comprehensive Protein and Phosphoprotein Interactome of the Arabidopsis TOR Complex

open access: yesAdvanced Science, EarlyView.
The target of rapamycin (TOR) complex is a central plant growth regulator. Here, the protein–protein interactions underlying its various functions are mapped by pupylation‐based proximity‐labeling in Arabidopsis, using TOR complex subunits LST8‐1 and RAPTOR1, alongside TOR inhibitor FK506‐binding protein, as baits.
Shuai Zheng   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy