Results 61 to 70 of about 44,477 (234)

Imatinib decreases germ cell survival and germline stem cell proliferation in rodent testis ex vivo and in vitro

Andrology, EarlyView.
Abstract Background Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has adverse effects on developing testis, and imatinib‐treated male patients have been reported to have reduced sperm counts.
Anna Eggert, Sini Laasanen, Mirja Nurmio, Aida Wahlgren, Kirsi Jahnukainen, Kim Eerola, Miisael Nieminen, Opeyemi Olotu, Noora Kotaja, Juho‐Antti Mäkelä, Jorma Toppari   +10 more
wiley   +1 more source

Survivability model for reconfigurable service carrying network based on the stochastic Petri net

Tongxin xuebao, 2016
Aiming at the defect that the security attribute of RSCN couldn't be described with measurement,a survivabil-ity model for RSCN was proposed based on the stochastic Petri net.Firstly,a non-Markovian stochastic Petri net for RSCN was proposed,and then the
Liang ZHAO, Hong ZOU, Xiao-hui ZHANG
doaj   +2 more sources

Biodiversity in mountain soils above the treeline

Biological Reviews, EarlyView.
ABSTRACT Biological diversity in mountain ecosystems has been increasingly studied over the last decade. This is also the case for mountain soils, but no study to date has provided an overall synthesis of the current state of knowledge. Here we fill this gap with a first global analysis of published research on cryptogams, microorganisms, and fauna in ...
Nadine Praeg, Michael Steinwandter, Davnah Urbach, Mark A. Snethlage, Rodrigo P. Alves, Martha E. Apple, Peter Bilovitz, Andrea J. Britton, Estelle P. Bruni, Ting‐Wen Chen, Kenneth Dumack, Fernando Fernandez‐Mendoza, Michele Freppaz, Beat Frey, Nathalie Fromin, Stefan Geisen, Martin Grube, Elia Guariento, Antoine Guisan, Qiao‐Qiao Ji, Juan J. Jiménez, Stefanie Maier, Lucie A. Malard, Maria A. Minor, Cowan C. Mc Lean, Edward A. D. Mitchell, Thomas Peham, Roberto Pizzolotto, Andy F. S. Taylor, Philippe Vernon, Johan J. van Tol, Donghui Wu, Yunga Wu, Zhijing Xie, Bettina Weber, Paul Illmer, Julia Seeber   +36 more
wiley   +1 more source

Analyzing the Behavior of Neuronal Pathways in Alzheimer's Disease Using Petri Net Modeling Approach

Frontiers in Neuroinformatics, 2018
Alzheimer's Disease (AD) is the most common neuro-degenerative disorder in the elderly that leads to dementia. The hallmark of AD is senile lesions made by abnormal aggregation of amyloid beta in extracellular space of brain.
Javaria Ashraf, Jamil Ahmad, Amjad Ali, Zaheer Ul-Haq   +3 more
doaj   +1 more source

Estimates of cycle times in stochastic petri nets [PDF]

, 2005
Disponible dans les fichiers attachés à ce ...
Baccelli, François, Konstantopoulos, Panagiotis   +1 more
openaire   +2 more sources

The Roles of Plasticity and Selection in Rapid Phenotypic Changes at the Pacific Oyster Invasion Front in Europe

Molecular Ecology, EarlyView.
ABSTRACT Invasive species present significant management challenges worldwide due to their ability to rapidly adapt to novel environments. The Pacific oyster Crassostrea gigas, a globally distributed invasive species, arrived in western Sweden in 2006 but has not yet colonised the low salinity waters of the Baltic Sea, presumably because low salinities
Alexandra Kinnby, Chloé Robert, Jonathan N. Havenhand, Göran Broström, Luc Bussière, Pierre De Wit   +5 more
wiley   +1 more source

Resources Modulate Developmental Shifts but Not Infection Tolerance Upon Co‐Infection in an Insect System

Molecular Ecology, EarlyView.
ABSTRACT Energetic resources within organisms fuel both parasite growth and immune responses against them, but it is unclear whether energy allocation is sufficient to explain changes in infection outcomes under the threat of multiple parasites. We manipulated diet in flour beetles (Tribolium confusum) infected with two natural parasites and used a ...
Nora K. E. Schulz, Danial Asgari, Siqin Liu, Stephanie S. L. Birnbaum, Alissa M. Williams, Arun Prakash, Ann T. Tate   +6 more
wiley   +1 more source

Assessment of the Availability of an Offshore Installation by Stochastic Petri Net Modeling

Communications, 2014
The purpose of this article is to illustrate the combination of stochastic Petri nets and Monte Carlo simulation approach for the evaluation of the production availability of a multi-state, multi-output offshore installation with operational loops.
Radim Bris
doaj   +1 more source

Gene Flow Disruption and Population Declines in a Soil Arthropod in Fragmented Habitats

Molecular Ecology, EarlyView.
ABSTRACT The intensification of land use over past millennia has accelerated habitat loss and fragmentation. This is hypothesized to lead to reductions in population sizes and restrictions in gene flow, processes that amplify genetic drift with profound negative impacts on species and populations.
Tammy Ai Tian Ho, Jeppe Bayer Pedersen, Anne Aagaard, Mads F. Schou, Jesper Bechsgaard, Derek Corcoran, Tove Hedegaard Jørgensen, Signe Normand, Trine Bilde   +8 more
wiley   +1 more source

A Three‐Stage Model of the Maturation of Nascent Policy Subsystems Toward Stable Advocacy Coalitions, With Evidence From the UK's Response to COVID‐19

Policy Studies Journal, EarlyView.
ABSTRACT Policy subsystems are comprised of competing advocacy coalitions, in which public and private political actors with shared belief systems learn from each other and coordinate their strategies in the pursuit of influencing policy making in their favor.
Kristijan Garic, Philip Leifeld
wiley   +1 more source