Results 171 to 180 of about 4,616 (278)

Mechanoadaptation via Myosin Cytoplasmic Redistribution Protects Circulating Tumor Cells From Shear‐induced Death During Hematogenous Dissemination

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang   +10 more
wiley   +1 more source

Sequential Monte Carlo with likelihood tempering and parallel implementation for uncertainty quantification

open access: yesAIChE Journal, Volume 72, Issue 6, June 2026.
Abstract Bayesian estimation enables uncertainty quantification, but analytical implementation is often intractable. As an approximate approach, the Markov Chain Monte Carlo (MCMC) method is widely used, though it entails a high computational cost due to frequent evaluations of the likelihood function.
Tatsuki Maruchi   +2 more
wiley   +1 more source

Topological Graph Neural Networks: A Novel Approach for Geometric Deep Learning

open access: yesApplied AI Letters, Volume 7, Issue 2, June 2026.
This graphical abstract illustrates the Topological Graph Neural Network (TopGNN) architecture. It demonstrates a parallel processing approach where an input graph is simultaneously analyzed by a standard GNN Encoder to capture local node features and by Persistent Homology to extract global topological features (like cycles and voids), visualized as a
Amarjeet   +7 more
wiley   +1 more source

Geometric Stabilization of Biomolecular Chirality in Open Systems

open access: yesChirality, Volume 38, Issue 6, June 2026.
Entropic topology favors orientation‐preserving deformations in molecular configuration space, leading to a spontaneous statistical bias toward right‐handed α$$ \alpha $$‐helices. The figure illustrates how configurations with positive determinant (dextral) occupy a larger accessible volume of microstates, providing a purely geometric‐entropic ...
Vicente Domínguez‐Arca
wiley   +1 more source

Analysis of a Multimedia Stream using Stochastic Process Algebra

open access: yes
. It is now well recognised that the next generation of distributed systems will be distributed multimedia systems. Central to multimedia systems is quality of service, which defines the non-functional requirements on the system.
J.W. Bryans, H. Bowman, J. Derrick
core  

A goodness‐of‐fit test for regression models with discrete outcomes

open access: yesCanadian Journal of Statistics, Volume 54, Issue 2, June 2026.
Abstract Regression models are often used to analyze discrete outcomes, but classical goodness‐of‐fit tests such as those based on the deviance or Pearson's statistic can be misleading or have little power in this context. To address this issue, we propose a new test, inspired by the work of Czado et al.
Lu Yang   +2 more
wiley   +1 more source

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