Results 121 to 130 of about 2,939,863 (258)
Advanced Science, EarlyView.Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao +10 more
wiley +1 more source
Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery
Advanced Science, EarlyView.A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li +9 more
wiley +1 more source
Multipower Variation and Stochastic Volatility [PDF]
In this brief note we review some of our recent results on the use of high frequency financial data to estimate objects like integrated variance in stochastic volatility models.
Neil Shephard, Ole Barndorff-Nielsen
core
Advanced Science, EarlyView.An AI‐enabled digital twin framework integrates wearable EMG sensing with hierarchical multi‐domain fusion to classify chronic ankle instability, distinguish clinically relevant subtypes, and generate continuous motor function scores. Clinically interpretable functional stratification and SHAP‐based biomarker analysis provide transparent decision ...
Tianle Jie +12 more
wiley +1 more source
Applying regression quantiles to farm efficiency estimation [PDF]
This article is concerned with the methodological question of frontier production functions estimation for agriculture, and the appropriateness of regression quantiles, as a useful semi-parametric approach.
Nitsi, Elisavet I., Kaditi, Eleni A.
core
Rainfall Shapes the Diversity of Soil Nitrogen‐Fixing Microorganisms Worldwide
Advanced Science, EarlyView.This study reveals the distinctive pattern and mechanism of rainfall driving the global biodiversity and biogeography of soil potential N‐fixing microorganisms, and constructs the theoretical framework. The results guide us on how to maintain ecosystem productivity under future climate changes (e.g., whether a specific region needs more N fertilizers ...
Bin Hua +18 more
wiley +1 more source
Multiphoton Quantum Reservoirs For Robust Multidimensional Computing
Advanced Science, EarlyView.Projective measurements reveal hidden multidimensional quantum networks within classical multiphoton fields, enabling robust quantum reservoirs for room‐temperature quantum simulation, prediction, and information processing. These networks transform noisy classical photonic platforms into scalable quantum computational architectures.
Mingyuan Hong +10 more
wiley +1 more source
Asymptotics of Least Trimmed Squares Regression [PDF]
High breakdown-point regression estimators protect against large errors both in explanatory and dependent variables.The least trimmed squares (LTS) estimator is one of frequently used, easily understandable, and thoroughly studied (from the robustness ...
Cizek, P.
core
Advanced Science, EarlyView.MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo +6 more
wiley +1 more source
Impact Of Couple Protection Rate On Birth Rate : A Stochastic Linear Regression Model
Indian Journal of Community Medicine, 1992 Couple Protection Rate is one of the proximate determinants of fertility : Since fertility is affected by a number of socio-cultural and biological factors, an increase in contraceptives acceptance need not necessarily be associated with a decline in ...
Singh A.S +3 more
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