Results 121 to 130 of about 1,446,606 (252)

Tradeoff between speed and robustness in primordium initiation mediated by auxin-CUC1 interaction

Nature Communications
Robustness is the reproducible development of a phenotype despite stochastic noise. It often involves tradeoffs with other performance metrics, but the mechanisms underlying such tradeoffs were largely unknown.
Shuyao Kong, Mingyuan Zhu, David Pan, Brendan Lane, Richard S. Smith, Adrienne H. K. Roeder   +5 more
doaj   +1 more source

Volatile Memristive Devices With Tunable Temporal Dynamics For Event‐Based Sensing

Advanced Materials, EarlyView.
Tunable volatile memristive devices can serve various neural‐inspired tasks that require different time windows of information retention. The ionic‐based volatility of the presented Pt/a‐STO/TaOx/Ta device stack can be reproducibly and controllably tuned in multiple ways.
Dimitrios Spithouris, Johannes Hellwig, Hugh Greatorex, Clemens Wittberg, Panagiotis Koutsogiannis, César Magén, Elisabetta Chicca, Regina Dittmann   +7 more
wiley   +1 more source

Batch Correction and Comparison of Intracellular Signaling Among Multiple Rheumatic and Inflammatory Diseases

Journal of Probability and Statistics
Assays that measure intracellular signaling can provide an especially mechanistic assessment of cellular states and are thereby useful for uncovering cellular physiology.
Tyson H. Holmes, Michael Couse, Yael Rosenberg-Hasson, Rosemary Fernandez, Ajay Fernandez, Kavita Mathi, Joel M. Guthridge, Judith A. James, Julie M. Yabu, Francois Haddad, P. J. Utz, Antonio Hardan, C. Garrison Fathman, Mark M. Davis, Holden T. Maecker   +14 more
doaj   +1 more source

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Disordered DNA methylation leads to targetable transcriptional plasticity in ATRT

Acta Neuropathologica Communications
Atypical teratoid rhabdoid tumor (ATRT) is a highly aggressive but genetically simple pediatric central nervous system tumor, defined by biallelic inactivation of the chromatin regulator SMARCB1 with remarkably few other cooperating mutations.
Ashley R. Tetens, Tyler R. Findlay, Jordyn Craig-Schwartz, Athanasia Liapodimitri, Oscar Camacho, Kegan O. Skalitzky, Adrian Idrizi, Rakel Tryggvadottir, Kayleigh Lunsford, Eric H. Raabe, Michael A. Koldobskiy   +10 more
doaj   +1 more source

Iterative Selection of DNA Nanostructures for Cellular Uptake

Advanced Materials, EarlyView.
DNA nanostructures are promising cell targeting delivery vehicles for therapeutics, but the targeting behavior is not fully understood. In this study, libraries of DNA nanostructures that can be amplified and sequenced are combined with cellular uptake as a selection pressure to iteratively refine DNA structures taken up in cells to better understand ...
Anjali Rajwar, Lisa Eichhorn, Jakub Palacka, Sandra Ly, Erik Benson   +4 more
wiley   +1 more source

Multivariate concave and convex stochastic dominance [PDF]

Stochastic dominance permits a partial ordering of alternatives (probability distributions on consequences) based only on partial information about a decision maker’s utility function.
EECKHOUDT, Louis, WINKLER, Robert L., DENUIT, Michel, TSETLIN, Ilia   +3 more
core  

Descriptors to Dynamics: A Materials and Device Perspective on in‐Materio Physical Reservoir Computing for Neuromorphic Edge Intelligence

Advanced Materials, EarlyView.
Intrinsic material dynamics are harnessed as computational resources for neuromorphic in‐materio physical reservoir computing. Defects, ionic motion, interfaces, percolation, geometry, and biasing shape transient states that provide fading memory, nonlinearity, and high‐dimensional projection for simple readout. A descriptor‐to‐dynamics framework links
Kshitij RB Singh, Alif Syafiq Kamarol Zaman, Muzhen Xu, Yuki Usami, Saptarshi Das, Hirofumi Tanaka   +5 more
wiley   +1 more source

Dual‐State Programmable Oxide Transistor for Time‐Based Cryptography

Advanced Materials, EarlyView.
A DUPOT enables independently tunable Vth and Isat depending on gate bias polarity, producing three‐dimensional dynamical behavior within a transfer characteristic. This behavior originates from charge trapping and oxygen‐ion migration in the HfO2 layer.
Huisu Noh, Min Gu Lee, Hwayoung Kim, Myeongchan Ko, Jungwan Noh, Taewook Go, Jingyao Yu, Sang‐Hee Ko Park, Himchan Cho, Kyung Min Kim   +9 more
wiley   +1 more source

Body-wide synchronization of insulin-signaling dependent DAF-16/FOXO nuclear translocation pulses correlated with C. elegans growth

Nature Communications
Insulin signaling is the core pathway regulating body growth, but the dynamics of insulin signaling across an organism has not been studied experimentally. By imaging C.
Burak Demirbas, Olga Filina, Timo Louisse, Ananya Natarajan, Yvonne Goos, María Antonia Sánchez-Romero, María Olmedo, Jeroen S. van Zon   +7 more
doaj   +1 more source