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Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

Advanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang, Song‐Zuo Xie, Yong‐Zhou Luo, Xin‐Pei Deng, Xi‐Rong Tan, Ze‐Geng Chen, Ling‐Xing Zeng, Gong Chen, Pei‐Rong Ding, Zhi‐Zhong Pan, Rong‐Xin Zhang   +10 more
wiley   +1 more source

Precision and Error Propagation in Static MEMS-IMU Inertial Navigation: A Stochastic Time-Series Analysis. [PDF]

Sensors (Basel)
Kariminejad MM, Sharifi MA, Mostafavi MA, Amiri-Simkooei A.   +3 more
europepmc   +1 more source

Network architecture determines delay robustness in the spindle assembly checkpoint. [PDF]

Sci Rep
Ibrahim B.
europepmc   +1 more source

Deciphering global patterns of marine microbial community assembly and network stability. [PDF]

mSystems
Ravikumar P, Ravindran A, Raman K.
europepmc   +1 more source

New adaptive memory stochastic fractional operators and their applications in computational intelligence. [PDF]

Sci Rep
Khan TU, Al-Juaid BS, Markarian C.
europepmc   +1 more source

Stochastic three-term conjugate gradient: a third-order curvature approximation correction algorithmic framework for machine learning. [PDF]

Sci Rep
Liu J, Yuan G, Mo Z.
europepmc   +1 more source

Nonlinear response mechanisms of microbial communities to coral reef biogeomorphy in the South China Sea. [PDF]

Appl Environ Microbiol
Long S, Yang Z, Zeng C, Yang H, Cao L, Wang D, Liu Y, Lin Q, Zheng Y.   +8 more
europepmc   +1 more source

Degradation-constrained multi-agent reinforcement learning with centralized training and decentralized execution for vehicle-to-grid optimization in renewable-dominated distribution networks. [PDF]

Sci Rep
Shiferaw Y, Kiros M, Yeneneh K, Sufe G.
europepmc   +1 more source

Delay-Dependent Exponential Stability of Neutral Stochastic Delay Systems [PDF]

IEEE Transactions on Automatic Control, 2009
This paper studies stability of neutral stochastic delay systems by linear matrix inequality (LMI) approach. Delay dependent criterion for exponential stability is presented and numerical examples are conducted to verify the effectiveness of the proposed
Xuerong Mao
exaly   +5 more sources

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Stability and stabilization of homogeneous stochastic systems

52nd IEEE Conference on Decision and Control, 2013
This study considers homogeneous stochastic systems and shows their stability and stabilization. We define a homogeneous stochastic system as an extension of a homogeneous deterministic system. We show that homogeneous systems can exhibit exponential stability or finite-time stability according to the degree of homogeneity.
Kenta Hoshino, Yuh Yamashita, Yûki Nishimura, Daisuke Tsubakino   +3 more
openaire   +1 more source