Results 41 to 50 of about 154,277 (267)
Chattering and congestion collapse in an overload switching control
Stochastic Systems, 2016 Routing mechanisms for stochastic networks are often designed to produce state space collapse (SSC) in a heavy-traffic limit, i.e., to confine the limiting process to a lower-dimensional subset of its full state space.
Ohad Perry, Ward Whitt
doaj +1 more source
A theory of stochastic systems part I: Stochastic automata
Information and Computation, 2005 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Pedro R. D'Argenio, Joost-Pieter Katoen
openaire +4 more sources
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Moderate deviations for recursive stochastic algorithms
Stochastic Systems, 2015 We prove a moderate deviation principle for the continuous time interpolation of discrete time recursive stochastic processes. The methods of proof are somewhat different from the corresponding large deviation result, and in particular the proof of the ...
Paul Dupuis, Dane Johnson
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Brownian inventory models with convex holding cost, Part 1: Average-optimal controls
Stochastic Systems, 2014 We consider an inventory system in which inventory level fluctuates as a Brownian motion in the absence of control. The inventory continuously accumulates cost at a rate that is a general convex function of the inventory level, which can be ...
Jim Dai, Dacheng Yao
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Compositional Abstraction for Stochastic Systems [PDF]
, 2009 We propose to exploit three-valued abstraction to stochastic systems in a compositional way. This combines the strengths of an aggressive state-based abstraction technique with compositional modeling. Applying this principle to interactive Markov chains yields abstract models that combine interval Markov chains and modal transition systems in a natural
Katoen, Joost P. +2 more
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Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Models with hidden regular variation: Generation and detection
Stochastic Systems, 2015 We review the notions of multivariate regular variation (MRV) and hidden regular variation (HRV) for distributions of random vectors and then discuss methods for generating models exhibiting both properties concentrating on the non-negative orthant in ...
Bikramjit Das, Sidney Ira Resnick
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Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source