Results 121 to 130 of about 413,007 (211)

Perspective: Hollow Core Optical Fibres for Ultraviolet and Visible Wavelengths

open access: yesAdvanced Science, EarlyView.
Hollow core optical fibres bypass material constraints that limit optical fibres at ultraviolet and visible wavelengths. However, their challenging fabrication has limited their development, and significant gains in performance remain possible. In this perspective we outline approaches to enable the next generation of fibres for shorter wavelengths ...
Robbie Mears   +5 more
wiley   +1 more source

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

open access: yesAdvanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao   +8 more
wiley   +1 more source

A Modular DNAzyme for Precise Visualization and Intervention of Alternative Splicing Isoforms in Live Cells

open access: yesAdvanced Science, EarlyView.
A Stringent dUPlex‐activated Error Robust (SUPER) DNAzyme system enables real‐time imaging of alternative mRNA splicing (e.g., Bcl‐xL/Bcl‐xS) in living cells via target‐triggered split‐DNAzyme reassembly and dual‐color fluorescence. It also achieves mRNA‐selective knockdown through DNAzyme‐based gene regulation, serving as a versatile tool for splicing
Mengru Lin   +6 more
wiley   +1 more source

An Elastocaloric Polymer with Ultra‐High Solid‐State Cooling via Defect Engineering

open access: yesAdvanced Science, EarlyView.
This work reports a defect‐engineering strategy that enables a record‐high adiabatic temperature change of up to 8.14 ± 1.76 °C in elastomers at an elevated temperature above 65 °C. Combined experimental and theoretical efforts reveal that increasing dangling‐chain defects nonmonotonically impacts the elastocaloric cooling performance of polymers due ...
Zhaohan Yu   +11 more
wiley   +1 more source

Modification Strategies of Carbon‐Based Electrodes From Structural Regulation to Multifunctional Integration

open access: yesAdvanced Science, EarlyView.
Tracing the evolution from structural regulation to multifunctional integration, this paper systematically analyzes modification strategies for carbon‐based electrodes. It evaluates how element doping, surface functionalization, and composite material design affect the electrode performance, and offers perspectives on future applications and challenges
Yunlei Wang   +4 more
wiley   +1 more source

Superspreading and the evolution of virulence. [PDF]

open access: yesPLoS Comput Biol
O'Neill X   +5 more
europepmc   +1 more source

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