Results 11 to 20 of about 258 (209)

Simplified stochastics calculus with applications in Economics and Finance [PDF]

, 2020
The paper introduces a simple way of recording and manipulating general stochastic processes without explicit reference to a probability measure. In the new calculus, operations traditionally presented in a measure-specific way are instead captured by ...
Černý, A., Ruf, Johannes, Ruf, J., Černý, Aleš   +3 more
core   +1 more source

Telephone Call Centers: Tutorial, Review, and Research Prospects [PDF]

, 2003
Telephone call centers are an integral part of many businesses, and their economic role is significant and growing. They are also fascinating sociotechnical systems in which the behavior of customers and employees is closely intertwined with physical ...
Mandelbaum, A., Noah Gans, Koole, G.M., Koole, Ger, Koole, G.M.; id_orcid, Avishai Mandelbaum, Gans, Noah, Gans, N., Ger Koole, Mandelbaum, Avishai   +9 more
core   +1 more source

QoS-aware bandwidth provisioning for IP network links [PDF]

, 2006
Current bandwidth provisioning procedures for IP network links are mostly based on simple rules of thumb, using coarse traffic measurements made on a time scale of e.g., 5 or 15 minutes.
Venemans, P., Aiko Pras, Berg, H. van den, Pieter Venemans, van de Meent, R., Pras, A., Michel Mandjes, Mandjes, Michel, Remco van de Meent, Meent, R. van de, Mandjes, M.R.H., Venemans, Pieter, Roijers, Frank, Pras, Aiko, Berg, H., Roijers, F. (Frank), Roijers, F., Venemans, P.H.A., Mandjes, M.R.H. (Michel), Meent, R., van den Berg, H., van den Berg, Hans Leo, Frank Roijers, Hans van den Berg, Altman, E   +24 more
core   +3 more sources

Analysis of operational risk of banks – catastrophe modelling [PDF]

, 2007
Nowadays financial institutions due to regulation and internal motivations care more intensively on their risks. Besides previously dominating market and credit risk new trend is to handle operational risk systematically. Operational risk is the risk of
Homolya, Dániel, Benedek, Gábor
core   +1 more source

Ambulance dispatch center pilots proactive relocation policies to enhance effectiveness [PDF]

, 2018
In life-threatening emergency situations in which every second counts, the timely arrival of an ambulance can make the difference between survival and death.
Jagtenberg, C.J. (Caroline), Bhulai, Sandjai, Martin van Buuren, Bhulai, Sandjai; id_orcid, Thije van Barneveld, Buuren, Martin, Barneveld, Thije, Jagtenberg, Caroline; id_orcid, Rob van der Mei, Jagtenberg, Caroline, Sandjai Bhulai, Bhulai, S. (Sandjai), Mei, Rob, Caroline Jagtenberg, Mei, R.D. (Rob) van der, Van Buuren, Martin, Van Der Mei, Rob, Van Barneveld, Thije, Buuren, M. (Martin) van, Barneveld, T.C. (Thije) van   +19 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source