Results 51 to 60 of about 1,649,233 (306)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Household Debt, Stock Market Participation, and Stock Market Returns: A Mediation Analysis

open access: yes, 2023
This thesis investigates whether increases in household debt increase stock market participation, and consequently decrease stock market returns. The three-way link is investigated across the immediate, short, and medium term, income groups, and the ...
Moalafi, C.
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Justissimum. Amoris. Monumentum. Qvod. Commendando. Excolendæ. Rationis. Curam. Præcipue. In. Jurisprudentia. ... / Constituere. Voluit. Debuitqve. Lüderus. Mencken. Jctus. ...

open access: yes
Autopsie nach Ex. der ULB Sachsen-AnhaltVorlageform des Erscheinungsvermerks: Lipsiæ. Apud. Phil. Wilhelm. Stock. - Erscheinungsjahr der Datierung S.
Mencke, Lüder
core   +1 more source

Estimating Biological Reference Points of the Pink Shrimp, Farfantepenaeus notialis (Perez-Farfante, 1967) Targeted by Shrimp Trawlers in Sierra Leone

open access: yesÇanakkale Onsekiz Mart University Journal of Marine Sciences and Fisheries, 2022
Time series of catch and effort data for Farfantepenaeus notialis were analysed in ‘R’ using a data limited state-space Bayesian Catch-maximum Sustainbale Yield (CMSY) method for stock assessment from catch (tonnes) and abundance data (t/day).
Komba J. Konoyima
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Stock returns and volatility: Evidence from the Athens Stock market index

open access: yes, 2001
This paper investigates the volatility of the Athens Stock excess stock returns over the period 1990–1999 through the comparison of various conditional hetero-skedasticity models.
Apergis, Nicholas, Eleftheriou, Sofia
core  

Data for: Assessing the suitability of Imaging-PAM fluorometry for monitoring growth of benthic diatoms

open access: yes
tab delimited txt with the unprocessed data used in Stock et al. 'Assessing the suitability of Imaging-PAM fluorometry for monitoring growth of benthic diatoms'
Stock, W
core   +1 more source

Medicine Inventory Grouping using Clustering Data Mining

open access: yesIndonesian Journal of Information Systems, 2019
One of the main factors in health services is adequate medicine supplies. Puskesmas is one of the health services that is managed under the district and city health offices to serve patients every day.
Joanna Ardhyanti Mita Nugraha
doaj   +1 more source

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