Results 191 to 200 of about 22,403 (309)

Analysis of the risk spillover network of G20 stock markets based on transfer entropy and complex network approaches. [PDF]

PLoS One
Zou Y, Chen Q, Han J, Zhao L.
europepmc   +1 more source

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao, Lin Zhang, Gufang Shen, Yangfan Lv, Tianshu Fang, Ya Cao, Qiongyi Zhang, Feng Xu, Chungang Liu   +8 more
wiley   +1 more source

Comovements and Causality of Sector Price Indices: Evidence from the Egyptian Stock Exchange

Contributing to the meagre published literature on interrelationships amongst stock market sectors of an economy, the present study sets out to examine both the long-run and short-run aspects of the inter-sectoral linkages in the Egyptian stock market ...
Ahmed, Walid M.A.
core  

The cholinergic system exerts opposing effects on memory at different stages of disease progression in Alzheimer's and Down syndrome model systems. [PDF]

Alzheimers Dement
Lisgaras CP, Scharfman HE.
europepmc   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Coupled geomorphic and climate-driven biogeochemical processes regulate soil organic carbon stocks in agricultural terraces. [PDF]

Sci Adv
Zhao P, Fallu DJ, Doetterl S, Cucchiaro S, Tarolli P, Pears BR, Lang A, Mainka MF, Ou X, Whitaker J, Wang Z, Brown AG, Six J, Van Oost K.   +13 more
europepmc   +1 more source

Extra Climate Benefits From Afforestation Due to Reduced Forest Fragmentation in China

Advanced Science, EarlyView.
Afforestation in China reduced forest fragmentation in 2015, transforming 51.8 M ha of edge forests into interior forests. This enhanced carbon sequestration (1.4±0.2 Pg CO2e, a cooling biogeochemical effect), while reduced albedo (−0.9 Pg CO2e, a warming biophysical effect) partially offset the gain, yielding a net extra climate benefit of ...
Nan Meng, Wei Li, Philippe Ciais, Martin Brandt, Xiaowei Tong, Yanzheng Yang, Guofeng Shen, Wei Du, Lei Zhu, Yi Leng, Minxuan Sun, Mengjie Han, Xuemei Zhang, Jie Zhang, Nan Wang, Dan Tong, Chao Wu, Wenhao Dong, Shu Tao, Bo Pan   +19 more
wiley   +1 more source

Momentum, volume and investor sentiment study for u.s. technology sector stocks-A hidden markov model based principal component analysis. [PDF]

PLoS One
Li S.
europepmc   +1 more source

Long‐Term Ambient Benzene Exposure and Brain Disorders Among Urban Adults: Effect Modification by Genetic Susceptibility and Potential Mediation by Plasma Proteins

Advanced Science, EarlyView.
Low‐level ambient benzene exposure is associated with increased risks of multiple brain disorders in urban adults. Genetic susceptibility modifies these associations, while plasma proteomics points to potential biological pathways linking benzene exposure to adverse brain health.
Jianhui Guo, Xia Zhong, Petros Koutrakis, Carolina L. Zilli Vieira, Feifei Si, Yaqi Wang, Xinyao Lian, Yi Fan, Zhaokun Wang, Shaodan Huang, Jing Li   +10 more
wiley   +1 more source

The impact of probiotic administration in vivo on peritoneal mouse macrophages infected by Leishmania amazonensis ex vivo. [PDF]

Mem Inst Oswaldo Cruz
Broeck LVD, de Azevedo RS, Fiuza LFA, Batista MM, Cascabulho CM, Van de Velde E, Van Calenbergh S, Caljon G, Soeiro MNC.   +8 more
europepmc   +1 more source