Results 61 to 70 of about 27,301 (308)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Stock market liquidity and the rights offer paradox. [PDF]

open access: yes
This paper contributes to the resolution of the rights offer paradox, using a database of French SEOs. We first document higher direct flotation costs, but also improved stock market liquidity after public offerings and standby rights relative to ...
Koenig-Matsoukis, Laure   +2 more
core   +2 more sources

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Stock liquidity and default risk around the world

open access: yes, 2020
We document the negative effect of stock liquidity on default risk for a sample of 46 countries. We further find that default risk declines following the introduction of the Directive on Markets in Financial Instruments (MiFID)—an exogenous shock that ...
Huang, A   +4 more
core   +1 more source

FINANCIAL RISKS AND STOCK MARKET CRASHES: AN EMPIRICAL ANALYSIS OF THE TUNISIAN STOCK MARKET

open access: yesApplied Finance Letters, 2021
This study aims to investigate the effect of financial risks on the stock market crashes occurrence from 1999 to 2020. Using the windows method, we detect two stock market crises in the Tunisian stock market.
Haifa Hammami, Younes Boujelbene
doaj   +1 more source

How Does Split Announcement Affect Stock Liquidity? Evidence from Bursa Malaysia

open access: yesRisks, 2020
This study examines the impact of stock splits on stock liquidity in Bursa Malaysia from 2004–2018. The study uses event study methodology and investigates liquidity changes, the role of liquidity, and the relationship between abnormal returns and ...
S. Amir Tabibian   +2 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

PERUBAHAN LIKUIDITAS AKIBAT PEMECAHAN SAHAM: STUDI DI PASAR MODAL INDONESIA

open access: yesJurnal Economia, 2014
Abstrak: Perubahan Likuiditas Akibat Pemecahan Saham: Studi di Pasar Modal Indonesia. Penelitian ini ingin mengetahui pengaruh pemecahan saham terhadap likuiditas dalam jangka pendek; pengaruh pemecahan saham, ukuran perusahaan dan return saham secara ...
Muniya Alteza   +2 more
doaj  

The Relationship between Stock Liquidity Dimensions and Put Option Volume as a New Financial Instrument [PDF]

open access: yesراهبرد مدیریت مالی, 2017
The aim of this study was to evaluate the relationship between stock liquidity dimensions and put option volume vas a new financial instrument in Iran.
Ali Khozein
doaj   +1 more source

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