Zuranolone: A case study in (regulatory) rush to judgement?
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
Indicator from the graph Laplacian of stock market time series cross-sections can precisely determine the durations of market crashes. [PDF]
Kang ZT, Yen PT, Cheong SA.
europepmc +1 more source
Abstract Cooperative learning is a widely adopted teaching method to improve academic achievement. This review synthesises existing research on the use of cooperative learning within a school setting for pupils aged 11–16 years. Such a review has not been undertaken to date and will present an evidence base for educators considering implementation ...
Patricia Hampson +2 more
wiley +1 more source
Forecasting Stock Market Indices Using Integration of Encoder, Decoder, and Attention Mechanism. [PDF]
Thach TT.
europepmc +1 more source
Falling pupil numbers and school closures: Setting a research agenda for a new era of precarity
Abstract This paper explores the significant phenomenon of decreasing pupil numbers in England due to lower birth rates and the impact of a school closure on a school community. It then discusses how the sociology of education might research this major issue.
Eleanor Fagan, Alice Bradbury
wiley +1 more source
Association between stock market volatility and severe mental disorders: a multi-city time-series study. [PDF]
Hu J +10 more
europepmc +1 more source
Gaussian Processes for Predictive QSAR Modeling of Chromatographic Processes
ABSTRACT Chromatography is a key unit operation in the biopharmaceutical manufacturing process used for protein purification and polishing. Design and optimization of these processes are resource‐intensive resulting from the complex combinatorial design space.
Harini Narayanan +7 more
wiley +1 more source
Entropy as a Tool for the Analysis of Stock Market Efficiency During Periods of Crisis. [PDF]
Papla D, Siedlecki R.
europepmc +1 more source
Restoring Trust: Rebuilding the Forest Carbon Credit System Through Scientific Rigor
ABSTRACT As pivotal nature‐based climate solutions (NbCS), forests are increasingly recognized for their climate mitigation potential. However, this potential is undermined by fundamental flaws in current carbon credit systems. Our analysis identifies four interconnected systemic challenges: (1) subjective additionality assessments arising from ...
Xiaoqian Che, Shaokun Li
wiley +1 more source

