Results 251 to 260 of about 3,469,724 (345)

Metabolic fate of drugs of abuse and new psychoactive substances: A pilot study on a novel workflow using a zebrafish embryo model combined with human microdosing

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg   +7 more
wiley   +1 more source

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić   +4 more
wiley   +1 more source

Empowering young people: Powerful knowledge in economics

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Powerful knowledge in school economics is conceptualised as the blending of economics knowledge arising from grasping threshold concepts with expressions of disciplinary thinking in terms of the powers or capabilities that this knowledge can provide to students who possess it.
Emanuel Mizzi
wiley   +1 more source

Evidentiary Authority as a System: Johann Christoph Gatterer and the Collective Making of Historical Knowledge in the Eighteenth Century

open access: yesBerichte zur Wissenschaftsgeschichte, EarlyView.
How is historical evidence conveyed? How could an eighteenth‐century scholar vouch for the information stored on paper, drafted with the quill, and publicized in copperplate engravings or letterpress? In this article, I employ material and medial perspectives to reconstruct the multiple production stages of Johann Christoph Gatterer's Historia ...
André de Melo Araújo
wiley   +1 more source

Enhanced stock market forecasting using dandelion optimization-driven 3D-CNN-GRU classification. [PDF]

open access: yesSci Rep
Jagadesh BN   +6 more
europepmc   +1 more source

A Surface Plasmon Resonance‐Based Integrated Assay for Quantification and Glycosylation Characterization of Monoclonal Antibodies in Crude Heterogeneous Samples

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The rise in cancer, autoimmune, inflammatory, and infectious diseases in recent decades has led to a surge in the development of monoclonal antibodies (mAbs) therapies, now the most widely used family of biologics. To meet the growing global demand, biopharmaceutical industries are intensifying their production processes.
Ilona Metayer   +7 more
wiley   +1 more source

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