Results 211 to 220 of about 80,158 (312)

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Digital Leadership, Information Entropy, and Stock Price Volatility: Evidence from CEO Social Media Behavior. [PDF]

Entropy (Basel)
Zou Y, Tian J, Zhang Y, Shi G, Cai X.
europepmc   +1 more source

Evaluating effectiveness of risk minimization through healthcare professional surveys: A review of post‐authorization studies, 2022–2024

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Risk minimization measures (RMMs) are key regulatory tools to ensure safe medicinal product use. Regulatory guidelines recommend pre‐specifying the targets, or ‘thresholds’, for assessing RMM effectiveness. We aimed to review recent industry‐sponsored post‐authorization safety studies (PASS) that evaluated the effectiveness of RMMs ...
Kexin Zhu, William A. Blumentals, Froilan G. Celzo, G. Caleb Alexander, Lingyun Zhou, Juhaeri Juhaeri, Corinne Jouquelet‐Royer, Jian‐Yu E   +7 more
wiley   +1 more source

Intelligent system for portfolio optimization for novel volatility forecasting using machine learning. [PDF]

Sci Rep
Biswas T, Dey A, Mandal G, Ghosh N.
europepmc   +1 more source

Pharmacokinetic Assessment of Atazanavir and Favipiravir Following Echinacea Supplementation: A Controlled Herb–Drug Interaction Investigation

Biopharmaceutics &Drug Disposition, EarlyView.
Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Siva Nageswara Rao Gajula, Jeevan Sai Kallam, Aarika Kanukolanu, Ganesh Korada, Lakshmi Vineela Nalla   +4 more
wiley   +1 more source

Silicon wafers outperform batteries: efficiency heterogeneity and policy effects in China's photovoltaic industry. [PDF]

Sci Rep
Li WQ, Liu HL, Liu XY, Ren FR.
europepmc   +1 more source

Cooperative learning strategies to raise attainment in mathematics with pupils aged 11–16 years: A systematic literature review

British Educational Research Journal, EarlyView.
Abstract Cooperative learning is a widely adopted teaching method to improve academic achievement. This review synthesises existing research on the use of cooperative learning within a school setting for pupils aged 11–16 years. Such a review has not been undertaken to date and will present an evidence base for educators considering implementation ...
Patricia Hampson, Zhe. Li, Allen Thurston   +2 more
wiley   +1 more source

The application of DM-MSTP method on Tunisian financial market: 2024 case study. [PDF]

Front Artif Intell
Dhouib S, Abdelhedi M, Ellouz S, Ezzine H, Chabchoub H.   +4 more
europepmc   +1 more source

Falling pupil numbers and school closures: Setting a research agenda for a new era of precarity

British Educational Research Journal, EarlyView.
Abstract This paper explores the significant phenomenon of decreasing pupil numbers in England due to lower birth rates and the impact of a school closure on a school community. It then discusses how the sociology of education might research this major issue.
Eleanor Fagan, Alice Bradbury
wiley   +1 more source

Portfolio management based on value distribution reinforcement learning algorithm. [PDF]

Front Artif Intell
Yang Y, Wang T, Fu Y, Huang J, Zhou D.
europepmc   +1 more source