Results 141 to 150 of about 7,685 (262)

A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43

open access: yesAdvanced Science, EarlyView.
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg   +16 more
wiley   +1 more source

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

open access: yesAdvanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li   +8 more
wiley   +1 more source

Asymmetric Single‐Atom Catalysts Govern Diffusible and Non‐Diffusible Non‐Radical Pathways for Selective Degradation of Antibiotic Resistance Genes

open access: yesAdvanced Science, EarlyView.
Asymmetric single‐atom metal‐nitrogen‐carbon catalysts modulate the non‐radical pathway during peroxymonosulfate (PMS) activation. A fundamental contrast was revealed between diffusible singlet oxygen (1O2) and non‐diffusible electron‐transfer pathways (ETP) in antibiotic resistance gene (ARG) degradation.
Chen Gao   +6 more
wiley   +1 more source

Single‐Atom‐Enhanced Fully Inkjet‐Printed Electrochemical Sensor for Dopamine Detection

open access: yesAdvanced Science, EarlyView.
Fully inkjet‐printed paper‐based dopamine sensors are fabricated using nitrogen‐doped graphene acid functionalized with copper single atoms. The copper sites uniquely enhance dopamine oxidation through strong molecular adsorption, as verified by electrochemical measurements and DFT calculations. The approach highlights the potential of single‐atom inks
Martin‐Alex Nalepa   +11 more
wiley   +1 more source

Therapeutic Outcomes of Graduated and Progressive Compression in Chronic Venous Disorders: A Meta-Analysis. [PDF]

open access: yesCureus
Hassan Awaji HH   +10 more
europepmc   +1 more source

Beyond Traditional Phenolics: Disulfide Bonds for Performance Enhancement of Aerospace Ablation‐Resistant Materials from Processing to Recycling

open access: yesAdvanced Science, EarlyView.
The dynamic disulfide bonds facilitated the development of high‐performance aerospace ablation‐resistant materials. At moderate temperature, the dissociation and recombination of disulfide bonds ensured excellent processability, mechanical properties, and recycling ability of phenolic resin; at high temperature, cleavage of disulfide bonds produced ...
Yu Li   +9 more
wiley   +1 more source

A Monolithic Janus Hydrogel Pressure Sensor for Wearable Motion and Physiological Monitoring

open access: yesAdvanced Science, EarlyView.
This work reports a monolithic Janus hydrogel pressure sensor featuring integrated conductive PEDOT and insulating PEGDA layers. The fabricated device achieves a rapid response time, a wide operating range, and good cyclic durability. The sensor demonstrates robust performance in tracking dynamic human joint motions, offering a scalable strategy for ...
Syed Atif Ali   +7 more
wiley   +1 more source

On the Role of Preprocessing and Memristor Dynamics in Reservoir Computing for Image Classification

open access: yesAdvanced Electronic Materials, EarlyView.
ABSTRACT Reservoir computing (RC) is an emerging recurrent neural network architecture that has attracted growing attention for its low training cost and modest hardware requirements. Memristor‐based circuits are particularly promising for RC, as their intrinsic dynamics can reduce network size and parameter overhead in tasks such as time‐series ...
Rishona Daniels   +4 more
wiley   +1 more source

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