Results 191 to 200 of about 621,617 (245)

Therapeutic Outcomes of Graduated and Progressive Compression in Chronic Venous Disorders: A Meta-Analysis. [PDF]

open access: yesCureus
Hassan Awaji HH   +10 more
europepmc   +1 more source

Injectable Peptide‐Based Functional Amyloid Hydrogels as Tunable Depots for Sustained Drug Delivery

open access: yesAdvanced Science, EarlyView.
An injectable and tunable peptide‐based functional amyloid hydrogel provides sustained insulin release while preserving insulin stability and bioactivity. The hydrogel enables prolonged glycemic regulation in vivo, exhibits excellent biocompatibility, and shows no detectable IAPP and α‐Syn heterologous cross‐seeding, highlighting its potential as a ...
Ranjit Shaw   +4 more
wiley   +1 more source

Piezoelectric Amino Acid Salts with Halogen‐Based Coformers Produce Exceptional Force‐Generated Voltage Output

open access: yesAdvanced Science, EarlyView.
Amino acid‐based multicomponent crystals have emerged as high‐performance, environmentally sustainable piezoelectrics. In this work, the correlation of crystal packing, molecular polarization, and electromechanical response is uncovered through integrated experimental and computational approaches.
Krishna Hari   +2 more
wiley   +1 more source

SensEnhance: A Genetic Circuit for Converting Endogenous Mammalian Gene Signals Into High‐Dynamic‐Range Genetic Readouts

open access: yesAdvanced Science, EarlyView.
Here, we present SensEnhance, a modular genetic circuit that converts leaky, low‐dynamic‐range promoter signals into tightly controlled, high‐dynamic‐range outputs. Applied to mechanosensing and IL‐6‐responsive promoters, SensEnhance increases fold changes from 2.6‐ and 2.5‐fold in promoter‐only configurations to over 20‐ and 14‐fold, respectively ...
Miguel Baños   +4 more
wiley   +1 more source

Pharmacokinetic Tuning Redirects β‐Lapachone From NQO1 Bioactivation to Vimentin‐Targeted Oxidation in Cancer

open access: yesAdvanced Science, EarlyView.
Pharmacokinetic tuning acts as a programmable mechanistic switch for β‐lap. Sustained low‐concentration exposure redirects β‐lap from NQO1 bioactivation to direct oxidation of vimentin, driving disulfide crosslinking, proteasomal overload and ferroptosis.
Lei Dou   +5 more
wiley   +1 more source

Leg compression for preventing hypotension after spinal anesthesia in elderly hip fracture patients. [PDF]

open access: yesEur J Orthop Surg Traumatol
Kulachote N   +6 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy