Results 51 to 60 of about 530,869 (198)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Biophysical characteristics of medical compression stockings

open access: yes, 2007
Summary Aim: Haemodynamic effectivity of 13 compression stockings in correlation with its physical characteristics. Patients, methods: In a prospective study, 42 patients in clinical stage C1–4 were examined with dynamic mercury strain gauge ...
A. Ströhn, M. Jünger, H. M. Häfner
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Graded compression stockings in elective orthopaedic surgery

open access: yes, 2000
We recruited 89 patients who had hip or knee replacements to assess the performance of below-knee graded compression stockings. The pressure gradients generated by the stockings were measured and all patients had venography of the ipsilateral leg.
A. C. W. Hui   +5 more
core   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

An unusual presentation of autonomic dysreflexia-autonomic dysreflexia due to pneumatic stockings

open access: yesJournal of Neuroanaesthesiology and Critical Care, 2017
Autonomic dysreflexia is a potentially dangerous clinical emergency associated with spine injury at or above T6 level. Identification of triggering factor and its removal is a very important for the management of this condition.
Ankita Madan   +3 more
doaj   +3 more sources

The level of awareness and the attitude of patients recommended for use of compression stockings in Turkish society, and investigation of the factors affecting their use

open access: yesPatient Preference and Adherence, 2018
Şinasi Manduz,1 Fatih Ada,1 Yusuf Ada2 1Cardiovascular Surgery Department, Cumhuriyet University School of Medicine, Sivas, Turkey; 2Department of Business Administration, Cumhuriyet University Faculty of Economics and Administrative Sciences, Sivas ...
Manduz Ş, Ada F, Ada Y
doaj  

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

Sequential Compression Devices Versus Graduated Compression Stockings

open access: yes, 2016
This evidence-based practice research compares the outcomes of sequential compression devices and graduated compression stockings on the prevention of blood-clot related complications in the ...
Heisner, Brooke
core   +1 more source

Evaluation of Using Compression Stocking in Postoperative Patients

open access: yesFlorence Nightingale Journal of Nursing, 2019
Aim: The aim of this study is to evaluate the using of compression stockings in postoperative patients. Method: This descriptive study was conducted in a University hospital with participation of the general surgery department patients between ...
Zeynep KIZILCIK ÖZKAN   +2 more
doaj  

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