Results 171 to 180 of about 71,521 (262)

One‐Step Access to Ultra‐Bright Macrocyclic Oligo‐BODIPYs Featuring Long‐Lived Cyclic Excitons

open access: yesAngewandte Chemie, EarlyView.
Strong Fluorescence Meets Long Lifetimes: A template‐free, one‐step synthesis affords a series of methylene‐bridged macrocyclic oligo‐BODIPYs combining strong fluorescence with exceptionally long fluorescence lifetimes. Steady‐state and time‐resolved optical spectroscopy reveal unique excitonic coupling conditions and unusual size‐dependent ...
Lukas J. Patalag   +10 more
wiley   +2 more sources

To Greater Twist: A Kinetically Biased π‐Radical Cascade

open access: yesAngewandte Chemie, EarlyView.
π‐Radical cascades enable step‐economic construction of complex polycyclic aromatic frameworks. In this work, we show that a multifurcating pathway can be kinetically steered toward a single, more distorted product. This counterintuitive “falling‐upward” outcome arises from an intrinsic mechanistic bias, revealing a broader dimension of control in π ...
Yong Yang   +8 more
wiley   +2 more sources

Large Stokes shift fluorophores from <i>meta</i>-substituted zwitterions. [PDF]

open access: yesChem Sci
Hogan DT   +5 more
europepmc   +1 more source

A DNA G‐Quadruplex‐Targeting Ligand Suppresses c‐MYC Expression: Implications for Gemcitabine‑Resistant Pancreatic Cancer

open access: yesAngewandte Chemie, EarlyView.
PQB‐4, a fluorescent small‐molecule ligand that targets c‐MYC DNA G‐quadruplexes (G4s), showed marked synergy with gemcitabine in resistant PANC‐1 cells (CI = 0.027). In vivo, the ligand reduced tumor weight by 44% in a PANC‐1 xenograft model. These results highlight the therapeutic potential of c‐MYC DNA G4‐targeting ligands for treating gemcitabine ...
Bo‐Xin Zheng   +10 more
wiley   +2 more sources

Quantum-enhanced reconfigurable in-memory stochastic computing. [PDF]

open access: yesLight Sci Appl
Yang HZ   +7 more
europepmc   +1 more source

Prevalence and Risk Factors for Financial Toxicity Among Sarcoma Patients During and Following Treatment Across the Lifespan. [PDF]

open access: yesCancer Rep (Hoboken)
Robinson MJ   +21 more
europepmc   +1 more source

Genetically Encoding Stimulated Raman-Scattering Probes for Cell Imaging Using Infrared Fluorescent Proteins. [PDF]

open access: yesJ Phys Chem Lett
Regan D   +10 more
europepmc   +1 more source

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