Results 111 to 120 of about 9,375,548 (246)

Angela Stokes interview, 09 August 2017 [PDF]

open access: yes, 2017
Angela Stokes is the daughter of Louis Stokes and a graduate of the University of Maryland and Howard University Law School. She was Assistant Attorney General for the State of Ohio and a Cleveland Municipal Court Judge for twenty years.

core  

Quantitative Visualization of Intracellular Nanometabolism Using Peak‐Shifted Dual‐State Emissive FRET Nanoprobes

open access: yesAdvanced Science, EarlyView.
This study reveals the long‐elusive intracellular dissolution mechanism of carrier‐free nanomedicines. By utilizing peak‐shifted dual‐state emissive FRET nanoprobes (PDFNPs) that undergo a distinct ratiometric fluorescence peak shift upon disassembly, we achieve real‐time, quantitative tracking of dissolution kinetics in live cells.
Farsai Taemaitree   +18 more
wiley   +1 more source

Near‐Infrared Fluorescent PROTAC Enables Theranostic Imaging and Selective Tau Degradation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren   +11 more
wiley   +1 more source

Navier-Stokes Prediction of the Effect of the Skids on the Aerodynamics of Helicopter Fuselage in Forward Flight [PDF]

open access: yes, 2006
A series of three-dimensional Navier-Stokes computations were carried out with and without skids to investigate the influence of the skids on the flow field and aerodynamic forces acting on a helicopter fuselage in low Mach number forward flight under ...
Khier, Walid
core  

Pressure‐Tuned Superconducting Dome and Persistent Charge‐Density‐Wave Order in NdSeTe2

open access: yesAdvanced Science, EarlyView.
NdSeTe2 exhibits an unusual pressure‐tuned phase diagram in which charge‐density‐wave order does not disappear at optimal superconductivity. Instead, Raman spectroscopy reveals a transformation from long‐range to short‐range correlations that remain invisible to resistivity and persist across the entire superconducting dome.
Shuyang Wang   +6 more
wiley   +1 more source

Stability of fully developed pipe flow of a shear-thinning fluid that approximates the response of viscoplastic fluids

open access: yesApplications in Engineering Science
The stability of steady, fully developed flow in a long cylindrical pipe for a shear-thinning fluid (which approximates a class of viscoplastic materials) is studied using linear stability analysis. The eigenvalues of the frequency of the perturbation of
Mohan Anand   +2 more
doaj   +1 more source

Seeing the Chemistry of Biomolecular Condensates: In Situ Mapping of Composition and Water Content

open access: yesAdvanced Science, EarlyView.
Raman hyperspectral imaging combined with spectral phasor analysis enables a label‐free quantification of proteins, polymers and water density within individual biomolecular condensates. By transforming complex vibrational fingerprints into intuitive compositional maps, the approach reveals the high water content and structural heterogeneity of ...
E. Sabri   +3 more
wiley   +1 more source

A General High‐Throughput Mucus Microrheology Platform for Quantitative and Scalable Mucus Phenotyping

open access: yesAdvanced Science, EarlyView.
High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling   +18 more
wiley   +1 more source

Nonlinear Quantum Effects Drive Grotthuss Proton Conduction in Structured Electrolytes Based on Deep Eutectic Solvents

open access: yesAdvanced Science, EarlyView.
We demonstrate that the inverse relationship between viscosity and conductivity in structured electrolytes can be circumvented by leveraging their hydrogen bonding networks for Grotthuss proton transport. Using a mixture of imidazole and levulinic acid, we show that the existence of extended hydrogen‐bonded chains that can rapidly reorient result in ...
Benworth B. Hansen   +15 more
wiley   +1 more source

Polarization Holographic 4D Phenotyping Reveals Nanoplastic Induced Dysfunction in Zooplankton

open access: yesAdvanced Science, EarlyView.
Contaminant‐induced dysfunction in complex aquatic organisms remains difficult to resolve across scales. Polarization Holographic Imaging Microscopy (PHIM) integrates polarization‐sensitive holography with computational volumetric reconstruction for label‐free phenotyping of zooplankton in natural seawater, revealing that nanoplastic stress drives ...
Yuxing Li   +8 more
wiley   +1 more source

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