Results 171 to 180 of about 1,082,822 (338)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Gaseous interchange in the stomach in the anæsthetised animal
, 1922 Nora Edkins
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SOME ADDITIONAL REMARKS ON THE ETIOLOGY AND DIAGNOSIS OF ACUTE DILATATION OF THE STOMACH. [PDF]
, 1902 H. CAMPBELL THOMSON
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Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
A SUCCESSFUL CASE OF GASTRECTOMY FOR CARCINOMA OF THE PYLORUS AND LESSER CURVATURE OF THE STOMACH, [PDF]
, 1902 G. A. Syme
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Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Molecular Oncology, EarlyView.Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza +5 more
wiley +1 more source
THE SURGERY OF THE STOMACH. A HANDBOOK OF DIAGNOSIS AND TREATMENT [PDF]
, 1913 HERBERT J. PATERSON
openalex +1 more source