Results 111 to 120 of about 5,062,400 (385)

Global Burden of 5 Major Types Of Gastrointestinal Cancer.

Gastroenterology, 2020
BACKGROUND & AIMS There were an estimated 4.8 million new cases of gastrointestinal (GI) cancers and 3.4 million related deaths, worldwide, in 2018. GI cancers account for 26% of the global cancer incidence and 35% of all cancer-related deaths.
M. Arnold, C. Abnet, R. Neale, J. Vignat, E. Giovannucci, K. McGlynn, F. Bray   +6 more
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Follow-up after curative resection for gastric cancer. Is it time to tailor it? [PDF]

, 2017
There is still no consensus on the follow-up frequency and regimen after curative resection for gastric cancer. Moreover, controversy exists regarding the utility of follow-up in improving survival, and the recommendations of experts and societies vary ...
Antolino, L, Aurello, P, D'Angelo, F, Giulitti, D, Petrucciani, N, Ramacciato, G.   +5 more
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Increased stomach cancer risk following radiotherapy for testicular cancer

British Journal of Cancer, 2014
Background:Abdominal radiotherapy for testicular cancer (TC) increases risk for second stomach cancer, although data on the radiation dose–response relationship are sparse.Methods:In a cohort of 22 269 5-year TC survivors diagnosed during 1959–1987 ...
M. Hauptmann, S. Fosså, M. Stovall, F. V. Leeuwen, T. Johannesen, P. Rajaraman, E. Gilbert, Susan A. Smith, R. Weathers, B. Aleman, M. Andersson, R. Curtis, G. Dores, J. Fraumeni, P. Hall, E. Holowaty, H. Joensuu, M. Kaijser, R. Kleinerman, F. Langmark, Charles F. Lynch, E. Pukkala, H. Storm, L. Vaalavirta, A. W. Belt-Dusebout, L. Travis, L. Morton   +26 more
semanticscholar   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Partial intestinal obstruction caused by duodenal obstruction by the superior mesenteric artery and abdominal aorta in a middle-aged woman: A case report

Heliyon
A 55-year-old woman with non-small cell lung carcinoma complained of epigastric pain, bloating, anorexia and postprandial nausea and vomiting over a five-year period.
Xu Zhang, Wenyu Sun, Ming Yao, Qiu Xia, Qing Zhang, Shuai Guo, Lixia Ma, Ze Li   +7 more
doaj  

Analysis of the dependence of survival in patients with gastric cancer on the location and characteristics of the tumor

Patologìâ, 2013
Introduction In Ukraine the rate of gastric cancer is 23 cases per 100 thousand of population. Despite the stable decrease in morbidity and mortality, this pathology continues to be in the top five most common malignancies among men and in the ...
O. M. Levyk, K. V. Barannikov
doaj   +1 more source

Epidemiology and trend of stomach cancer mortality in Iran [PDF]

, 2016
Background and aims: Stomach cancer is one of the most common cancers and the second cause of deaths among cancers worldwide cancer in the world. This study aimed to estimate the rate and trend of death from stomach cancer in Iranian population between ...
Amoori, Neda., Enayatrad, Mostafa., Mahdavi, Sepideh.   +2 more
core