Results 71 to 80 of about 161,240 (242)

The examination of food and microplastics in the digestive tract of Cerberus rynchops

open access: yesArab Journal of Basic and Applied Sciences
Microplastics (MPs) represent one of the most significant global environmental issues due to their widespread use in consumer materials. The rapid growth of plastic product consumption leads to unmanaged waste separation and elimination.
Chompoonut Pengchui   +3 more
doaj   +1 more source

Sampling sufficiency in stomach content surveys of omnivorous fish species [PDF]

open access: yesZoologia (Curitiba)
Feeding research in fish has offered understanding into the ecology of individuals, populations, and ecosystems. In these studies, analyzing enough stomachs is crucial to determine a species’ diet. This research evaluates the number of stomachs needed to
Patrícia Santos Fráguas   +1 more
doaj   +1 more source

Updating salamander datasets with phenotypic and stomach content information for two mainland Speleomantes. [PDF]

open access: yesSci Data, 2021
Lunghi E   +6 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Clinic immunological comparison when studying erosive affections of gastro duodenal zone in patients with bronchial asthma

open access: yesБюллетень сибирской медицины, 2003
The aim of the work is to study the condition of the local immunity of stomach when there is bronchial asthma and the role of affection of some its factors in the formation of gastro duodenal pathology in this category of patients.
G. M. Chernyavskaya   +5 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Coexisting in the Surf Zone: Age and Feeding Habits of the Spotted Seabass (Dicentrarchus punctatus) and European Seabass (Dicentrarchus labrax) on the Gulf of Cádiz Beaches (Southwest Iberian Peninsula)

open access: yesFishes
Various commercial fish species utilize different coastal habitats as nurseries in their juvenile stages, with surf zones being particularly crucial due to the protection and abundant food resources they offer.
Carlos Rodríguez-García   +3 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

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