Results 141 to 150 of about 265,205 (305)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Histological effects of chronic administration of aqueous extract of Phyllanthus amarus on the stomach and the duodenum of Wistar rat

, 2011
Background: Phyllanthus amarus is a herbal agent commonly used for the treatment of several diseases including gastric ones. A systematic study about its toxic effects when chronically and excessively administered is still lacking.
Adjene, J.O., Abudu, I.E., Nwose, E.U.
core  

Chromatin Remodeling-Related PRDM1 Increases Stomach Cancer Proliferation and Is Counteracted by Bromodomain Inhibitor

Gastrointestinal (GI) cancers are some of the main public health threats to the world. Even though surgery, chemotherapy, and targeted therapy are available for their treatments, these approaches provide limited success in reducing mortality, making the ...
Yu-Hsuan Hung, Hui-Ching Wang, Mei-Ren Pan, Li-Tzong Chen   +3 more
core   +1 more source

Modern strategy of patient management in pre-cancer stomach diseases: diagnostic approaches and therapeutic possibilities

, 2021
Stomach cancer represents a serious medical and social problem, both for most of the countries, and for Russia. Patients with chronic atrophic gastritis or intestinal metaplasia have increased risk of stomach adenocarcinoma development.
L. B. Lazebnik, E. A. Lyalyukova
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Adaptive immunity at patients with chronic diseases of the stomach and intestine

, 2009
Aim of investigation. To determine the pathogenic significance of changes of general (adaptive) immunity in patients with chronic diseases of the stomach and intestine.Material and methods.
V. T. Ivashkin, N. L. Denisov
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Clinical impact of 24-hour pH-metry in esophageal and stomach diseases diagnostics and pharmacological drugs efficacy testing

, 2018
Aim of the article. To present the technique of twentyfour hour esophageal and stomach pH-metry, indications and contraindications to the study, interpretation o intraesophageal and intragastric pH-metry parameters. Summary.
Olga A. Storonova, A. S. Trukhmanov, V. T. Ivashkin   +2 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Dachengqi decoction for the treatment of acute pancreatitis: a comprehensive analysis based on metabolites, pharmacokinetics, and metabolites efficacy mechanisms

Frontiers in Pharmacology
Dachengqi decoction (DCQD) is a traditional Chinese medicine formula consisting of three botanical drugs and one mineral drug. It has anti-inflammatory, gastrointestinal motility, and microcirculation improvement effects.
Wen Guo, Wen Guo, Xiaobin Zhang, Xiaobin Zhang, Xin Zhou, Xin Zhou, Wangpeng Lan, Wangpeng Lan, Jianqin Liu, Yali Liu, Yali Liu, Li Li, Li Li, Zhi Li, Zhi Li, Zhi Li   +15 more
doaj   +1 more source