Results 101 to 110 of about 157,659 (296)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Risk Factors for Gastric Tumorigenesis in Underlying Gastric Mucosal Atrophy
Gut and Liver, 2017 Background/AimsAtrophic gastritis is considered a premalignant lesion. We aimed to evaluate the risk factors for gastric tumorigenesis in underlying mucosal atrophy.Methods : A total of 10,185 subjects who underwent upper gastrointestinal endoscopy ...
Ji Hyun Song +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Feasibility of a complete pancreatobiliary linear endoscopic ultrasound examination from the stomach [PDF]
, 2017 Background and study aims Linear endoscopic ultrasound (EUS) evaluation of the pancreaticobiliary system usually requires scanning from both the stomach and the duodenum.
Vinay Dhir +4 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Distal gastrectomy for gastric carcinoma in patients with diabetes mellitus: impact of reconstruction type on glucose tolerance [PDF]
, 2019 journal ...
808 +19 more
core +2 more sources
Zhongguo aizheng zazhi, 2014 Background and purpose: Itch protein is an established regulator of T cell immune response thresholds, belong to a class of E3 ubiquitin-transferring enzymes, widely involve in the ubiquitination of several key signaling molecules, such as ZAP70, P85 ...
粟英 +4 more
doaj
The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2017 A 67-year-old man underwent two endoscopic submucosal dissection procedures, one for gastric adenoma and one for early gastric cancer. The follow-up endoscopy showed metachronous recurrence at the anterior wall of the lower body, for which he underwent a
Chung Min Han +3 more
doaj +1 more source
Heterotopic Pancreas in the Stomach Masquerading Neoplasm
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2014 A 36-year-old male was referred to our hospital with a diagnosis of adenocarcinoma stomach on endoscopic biopsy while routinely being evaluated for acid peptic disease. Patient had past episodes of epigastric pain and nausea. The physical examination findings, routine blood tests and abdominal ultrasonography were unremarkable.
Manas R Baisakh +4 more
openaire +3 more sources