Results 51 to 60 of about 11,434 (220)

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang, Ngasin Lam, Xiaoming Huang, Yang Jiao   +3 more
wiley   +1 more source

Real‐World Effectiveness and Safety of Upadacitinib in Crohn's Disease: Insights From the Eneida Registry

United European Gastroenterology Journal, Volume 14, Issue 4, May 2026.
ABSTRACT Background Upadacitinib (UPA) is the first oral Janus kinase (JAK) inhibitor approved for the treatment of Crohn's disease (CD). Real‐world data, particularly from large nationwide cohorts, remain limited. This study aimed to evaluate the real‐world effectiveness, safety, and treatment persistence of UPA in patients with CD.
M. Iborra, B. Botella, M. D. Martín‐Arranz, D. Ceballos, C. Martínez‐Pascual, A. Garrido, P. Varela, M. Moreta, E. Brunet‐Mas, Y. González‐Lama, E. Rodríguez‐González, M. Vicuña, J. P. Gisbert, I. Ordás, F. Argüelles‐Arias, J. Tosca‐Cuquerella, R. Vicente‐Lidón, M. Sierra‐Ausín, I. Rodríguez‐Lago, D. Martín‐Rodríguez, J. M. Paredes, B. Sicilia, I. García de la Filia, N. Jiménez, M. Barreiro‐de Acosta, E. Betoré, I. Ferrer‐Bradley, L. García‐Alles, J. M. Huguet, S. Castellet‐Farrús, M. J. García, A. Gutiérrez‐Casbas, Á. Ponferrada‐Díaz, L. Ramos, M. Calafat, I. Vera, C. Suárez‐Ferrer, E. Fernández‐Velado, S. Rodríguez‐Sánchez, A. Mínguez, A. Mancebo, J. Barrio, S. Lario, D. R. de La Cruz, Alejandro Hernández‐Camba, C. Rodríguez‐Gutiérrez, M. Chaparro, E. Ricart, L. Almenara‐Michelena, A. Balaguer, E. Domènech, P. Nos   +51 more
wiley   +1 more source

Prevalence of recurrent aphthous ulceration in the Indian Population [PDF]

, 2014
Objective: Patients with an oral ulcer may present initially to a general physician or a dental practitioner. Majority of the ulcers are benign and resolve spontaneously but small proportions are malignant.
Bharati, Doni, Khandelwal, Suneet, Maheshwari, Sneha, Reddy, Niranjan, Santosh, Patil, Shruthi, D.   +5 more
core  

Real‐World Outcomes of Baricitinib and Ritlecitinib in Refractory Alopecia Areata: Response Predictors and Relapse After Discontinuation or Dose Reduction

The Journal of Dermatology, Volume 53, Issue 5, Page 746-757, May 2026.
ABSTRACT Baricitinib and ritlecitinib are newly approved systemic Janus kinase (JAK) inhibitors for severe, refractory alopecia areata (AA). Although clinical trials have demonstrated their efficacy, real‐world evidence remains limited, particularly regarding predictors of response and outcomes following treatment interruption or dose tapering.
Rina Hayashi, Saori Takamura, Tomoo Fukuda   +2 more
wiley   +1 more source

Advances in Crohn's Disease: A Comprehensive Review of Pathophysiology, Diagnosis, and Emerging Therapeutics

JGH Open, Volume 10, Issue 4, April 2026.
ABSTRACT Crohn's disease (CD) is a chronic inflammatory condition of the bowel with a rising global incidence. Its complex etiology involves genetic susceptibility, environmental factors, and alterations in the gut microbiota, leading to dysregulated immune responses.
Yoon‐Kyo An, Robert Gilmore, Graham Radford‐Smith, Jakob Begun   +3 more
wiley   +1 more source

The borax efficacy in the treatment of aphthous stomatitis

Medisur, 2023
Background: aphthous stomatitis is a chronic disease characterized by the non-keratinized oral mucosa ulceration, which presents acutely and painfully.Objective: to evaluate the efficacy of borax in the aphthous stomatitis treatment.Methods: an ...
Yolanda Iglesias Sanches, Julia Moya Martínez, Semiramis Garcia Gómez, Norelis García Lezcano   +3 more
doaj  

Developing a Measure to Assess General Knowledge for Coeliac Disease

Health Expectations, Volume 29, Issue 2, April 2026.
ABSTRACT Background The importance of establishing knowledge about coeliac disease relates to the increasing incidence of symptomatic individuals who are undiagnosed. Objectives This study aimed to develop and pilot a tool that could be used to measure general knowledge regarding coeliac disease.
Tiffany Lavis, K. Ann Horsburgh, Jacqueline F. Gould, Elizabeth Bingham Thomas   +3 more
wiley   +1 more source

Prevalence of recurrent aphthous ulceration experience in patients attending Piramird dental speciality in Sulaimani City [PDF]

, 2013
The aim of this study is to report the prevalence and risk factors of recurrent aphthous ulceration (RAU) in patients attending Piramird dental speciality for seeking dental treatment.
Abdullah, Mustafa Jamel
core   +1 more source

Dupilumab Treatment in Pemphigus: A Report of Three Cases and Literature Review

JEADV Clinical Practice, Volume 5, Issue 1, Page 254-257, March 2026.
Capsule summary Pemphigus vulgaris and foliaceus are rare autoimmune blistering diseases traditionally treated with corticosteroids, immunosuppressants, intravenous immunoglobulins, and rituximab. A subset of patients remains refractory or has contraindications to these conventional therapies. We present three cases of pemphigus treated with dupilumab.
José Javier Mateos Rico, Marta Gutiérrez Pascual, María Dolores Caro Gutiérrez, Cristina Marcos Rodríguez, Javier de Quadros Malagón, Francisco Javier Vicente Martín   +5 more
wiley   +1 more source

Therapeutic effectiveness of calendula jelly at 1% in patients with aphthous recurrent stomatitis

Medisan, 2021
Introduction: The officinalis L Calendula fluid extract and tincture is usually used as mouthwash dissolved in water for the treatment of patients with aphthous recurrent stomatitis. Taking into account the inconveniences that generate these formulations
Ana Ibis Bosch Nuñez, Maylen Maidelín Tejeda Bertot, Arileidis Moreno Montoya   +2 more
doaj