Results 51 to 60 of about 89,775 (291)

Incidence and Risk Factors for Radiotherapy-Induced Oral Mucositis Among Patients With Nasopharyngeal Carcinoma: A Meta-Analysis

Asian Nursing Research, 2023
SUMMARY: Purpose: To evaluate the incidence and identify the risk factors for radiotherapy-induced oral mucositis among patients with nasopharyngeal carcinoma. Methods: A meta-analysis was conducted. Eight electronic databases (Medline, Embase, Cochrane
Juejin Li, Chuanmei Zhu, Yun Zhang, Chang Guan, Qi Wang, Yuxin Ding, Xiaolin Hu   +6 more
doaj   +1 more source

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

Advanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie, Ziye Huang, Zhiyuan Zhang, Yiqiang Zhu, Xiaoqing Liu, Lei Wang, Tongyu Bi, Taizhen Liang, Jintao Lai, Meilin Hu, Guochang Qiu, Shiqi Xiao, Sen Liu, Yaoming Liu, Haiyue Rao, Tao Chen, Haojie Peng, Bin Zhang, Jia Tang, Qianying Li, Yaxin Li, Yuxin Hou, Weibo Yang, Hewei Jiang, Xiancai Ma   +24 more
wiley   +1 more source

Contact Stomatitis

Dermatologic Clinics, 1987
Allergic contact stomatitis may be difficult to distinguish from irritant stomatitis and may mimic the oral changes of a vitamin deficiency, certain anemias, uremic stomatitis, stomatitis nicotina, and even candidiasis. When these conditions have been ruled out, skin patch testing may be indicated.
openaire   +2 more sources

A Fish MDA5 Integrates Canonical RIG‐I and MDA5 Ligand Recognition

Advanced Science, EarlyView.
These results show that the large yellow croaker lacks RIG‐I, yet its MDA5 senses both 5′ppp‐dsRNA and long dsRNA. A flexible RNA‐capping loop in the MDA5 C‐terminal domain enables two ligand‐binding modes. This dual recognition signals through MAVS–STING–TBK1/IRF3 and induces type I interferons, revealing unexpected plasticity in vertebrate antiviral ...
Wenxing Li, Yuan Feng, Huazhi Chen, Jiamei Liu, Álvaro Fernández Montero, Jiangtao Gao, Jingqun Ao, Xinhua Chen   +7 more
wiley   +1 more source

The use of combined drugs as a component of complex therapy of inflammatory diseases of the pharynx: A review

Consilium Medicum
Unfortunately, the occurrence of various pathologies in the ENT organs still remains one of the pressing problems in global healthcare. The frequent manifestation of unwanted pathologies forces us to change methods, and sometimes to introduce something ...
Sergey Ya. Kosyakov, Ekaterina V. Pchelenok, Khava S. Usmanova   +2 more
doaj   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Beitrag zur Stomatitis aphthosa

, 1901
BEITRAG ZUR STOMATITIS APHTHOSA Beitrag zur Stomatitis aphthosa ([1]) Binding ( - ) Title page ([1]) Dedication ([3]) Chapter ([5]) Section (18) Litteratur. ( - ) Lebenslauf. ( - ) Binding ( -
Krug, Hugo
core   +1 more source

MEASUREMENT OF ANTIOXIDANT POWER OF MOUTHWASHES INDICATED IN STOMATITIS [PDF]

, 2015
Objective: Hospital formulations containing allopurinol and rebamipide are used in the prophylactic and therapeutic management of stomatitis,owing to their antioxidant powers. The objective of this study was to measure the antioxidant powers of Zyloric®
Sakurai, Shotaro, Matida, Yoshiaki, Sasaki, Nae, Wakui, Nobuyuki, Yamamura, Miho, Ando, Sakiko, Kobayashi, Ami   +6 more
core   +1 more source

Effectiveness of cryotherapy in preventing oral mucositis in pediatric cancer patients in Jordan: a randomized controlled trial [PDF]

Child Health Nursing Research
Purpose The study aimed to evaluate the effectiveness of cryotherapy in preventing oral mucositis in pediatric patients receiving chemotherapy. Methods An evidence-based practice project utilized a randomized control trial design with two groups ...
Khadeja Banat, Huda Al-Haja, Mariam Ananbeh, Eman Abdullah, Aladeen Alloubani   +4 more
doaj   +1 more source

Efficacy and Safety of Nanoencapsulated Sirolimus Plus Pegadricase: Results From the Randomized, Placebo‐Controlled Phase 3 Trials

Arthritis &Rheumatology, EarlyView.
Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf, Puja P. Khanna, Milan Petronijevic, Mamuka Lortkipanidze, Anand Patel, Kwabena Ayesu, Michael H. Pillinger, Atul Singhal, Joanna Sobierska, Jacquie Christie, Peter Traber, Rehan Azeem, Wesley DeHaan, Hugues Santin‐Janin, Bhavisha Desai, Alan Kivitz   +15 more
wiley   +1 more source