Results 21 to 30 of about 253,691 (218)

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Towards a Taxonomy Machine: A Training Set of 5.6 Million Arthropod Images

open access: yesData
The taxonomic identification of organisms from images is an active research area within the machine learning community. Current algorithms are very effective for object recognition and discrimination, but they require extensive training datasets to ...
Dirk Steinke   +15 more
doaj   +1 more source

The Increased Risk of Renal Stones in Patients With COVID-19 Infection

open access: yesPharmaceutical and Biomedical Research, 2022
Background: The novel coronavirus disease (caused by SARS-CoV-2) has become a disaster all over the world. Based on available evidence, the main organ infected by this virus is the respiratory system; however, various other vital systems can also be ...
Hossein Kasiri   +3 more
doaj  

Gritty sensation on catheter: A new clinical sign for self-diagnosis of stone formation in the continent urinary pouch

open access: yesIndian Journal of Urology, 2010
With more experience and better management, the incidence of complications like stone formation after continent urinary diversion is uncommon today.
Apul Goel   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Hacı Bayram Veli’nin Şiirlerinde İnsanın İkilemi

open access: yesTasavvuf İlmi ve Akademik Araştırma Dergisi, 2023
Anadolu tasavvuf geleneğinde günümüzde yadsınamaz derecede önem taşıyan şahsiyetlerden biri de Hacı Bayram Veli’dir. Tasavvufi kurum ve ekoller açısından farklı akisleri olan Hacı Bayram Veli’nin Türk toplumunun ürettiği farklı kültürel enstrümanlarda da
Musa Kaval
doaj  

Analyses of Urban Pavement Surface Temperatures

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2015
Heat islands are areas that have higher air temperatures than their surroundings. It has been proven that the use of certain types of pavement surface materials contributes to the occurrence of heat islands.
Aleksandra Deluka-Tibljaš   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

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