Results 51 to 60 of about 2,553,893 (339)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Reduction of Activation Energy Barrier of Stone-Wales Transformation in Endohedral Metallofullerenes

, 2005
We examine effects of encapsulated metal atoms inside a C$_{60}$ molecule on the activation energy barrier to the Stone-Wales transformation using {\it ab initio} calculations. The encapsulated metal atoms we study are K, Ca and La which nominally donate
D. Vanderbilt, E. Kaxiras, Gunn Kim, Jisoon Ihm, S. Han, Seungwu Han, Woon Ih Choi   +6 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Petrographic study of selected sculptural works of Jan Michałowicz from Urzędów

Budownictwo i Architektura, 2018
Nowadays, in order to determine whether given rock properties make it useful for specifi c purposes, the material is examined using relevant test equipment.
Małgorzata Ciosmak, Patrycja Rzęsa
doaj   +1 more source

English Studies as a Site for Healing: A Conversation about Place-Based and Indigenous Pedagogies in the English Classroom [PDF]

, 2017
This article summarizes a roundtable discussion from the 2016 Alaska Native Studies Conference among professors and students from two English Studies courses at the University of Alaska Anchorage: History of the English Language and History of Rhetoric ...
Brook Adams, Heather, Mack, Samantha, Nasruk Davis, Arlo, Nicolet-Lloyd, Hailey, Snoddy, Tayler, Stone, Jennifer   +5 more
core  

Electron Population Aging Models for Wide-Angle Tails [PDF]

, 1999
Color-color diagrams have been useful in studying the spectral shapes in radio galaxies. At the workshop we presented color-color diagrams for two wide-angle tails, 1231+674 and 1433+553, and found that the standard aging models do not adequately ...
A. Young, A.A. O’Donoghue, D.M. Katz-Stone, Katz-Stone, Katz-Stone, Katz-Stone, L. Rudnick, Tribble   +7 more
core   +3 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Energy prediction and optimization for robotic stereoscopic statue processing

Scientific Reports
Energy consumption has become one of the primary costs in the stone processing industry. Stereoscopic statue production, characterized by extensive material removal and prolonged cycles, consumes the most energy among stone products.
Xu-Hui Cheng, Fang-Chen Yin, Cong-Wei Wen, Ye Wang, Yi-Hao Li, Ji-Xiang Huang, Shen-Gui Huang   +6 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Intraluminal stone in a PD catheter : third world case

Bulletin de la Dialyse à Domicile, 2018
Only 2 cases of intraluminal peritoneal catheter lithiasis have been reported so far. A woman (68 years of age) on CAPD was admitted to hospital because of intermittent outflow obstruction of her peritoneal catheter.
Béatrice Champtiaux Dechamp, Lise Mandart, Pierre-Yves Durand   +2 more
doaj   +1 more source