Results 131 to 140 of about 124,521 (292)

Economy and status of Neolithic to Early Bronze age sites in the Southern Caucasus during the 6th‐3rd mill. BCE: The evidence from ground stone tools

, 2021
Caroline Hamon
openalex   +2 more sources

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

A late Middle Pleistocene Middle Stone Age sequence identified at Wadi Lazalim in southern Tunisia. [PDF]

Sci Rep, 2022
Cancellieri E, Bel Hadj Brahim H, Ben Nasr J, Ben Fraj T, Boussoffara R, Di Matteo M, Mercier N, Marnaoui M, Monaco A, Richard M, Mariani GS, Scancarello O, Zerboni A, di Lernia S.   +13 more
europepmc   +1 more source

DIMENSIONAL AND AGE STRUCTURE OF MOUNTAIN SIBERIAN STONE PINE FORESTS OF THE CIS-YENISEI SAYAN

, 2020
М.Е. КОНОВАЛОВА, E. G. Konovalova, E. N. Tsvetkov, D. D. Genov   +3 more
openalex   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Stone Age Yersinia pestis genomes shed light on the early evolution, diversity, and ecology of plague. [PDF]

Proc Natl Acad Sci U S A, 2022
Andrades Valtueña A, Neumann GU, Spyrou MA, Musralina L, Aron F, Beisenov A, Belinskiy AB, Bos KI, Buzhilova A, Conrad M, Djansugurova LB, Dobeš M, Ernée M, Fernández-Eraso J, Frohlich B, Furmanek M, Hałuszko A, Hansen S, Harney É, Hiss AN, Hübner A, Key FM, Khussainova E, Kitov E, Kitova AO, Knipper C, Kühnert D, Lalueza-Fox C, Littleton J, Massy K, Mittnik A, Mujika-Alustiza JA, Olalde I, Papac L, Penske S, Peška J, Pinhasi R, Reich D, Reinhold S, Stahl R, Stäuble H, Tukhbatova RI, Vasilyev S, Veselovskaya E, Warinner C, Stockhammer PW, Haak W, Krause J, Herbig A.   +48 more
europepmc   +1 more source

Archaeological biological mineralizations: A cutting-edge multi-proxy investigation on kidney stones from the Argaric Bronze Age civilization [PDF]

Robin Francotte, Camila Oliart Caravatti, Jennifer Bodin, Stéphan Rouzière, Cristina Rihuete Herrada, Eva Celdrán Beltrán, Vicente Lull, Brecht Laforce, Jacob I. Griffith, Vince Lazlo, Christophe Snoeck, Steven Goderis, Michel Daudon, Emmanuel Letavernier, Dominique Bazin, Rafael Micó Pérez, Frederik Tielens   +16 more
openalex   +1 more source

New investigations at the Middle Stone Age site of Pockenbank Rockshelter, Namibia [PDF]

, 2016
Isabell Schmidt, Götz Ossendorf, Elena A. Hensel, Olaf Bubenzer, Barbara Eichhorn, Lothar Gessert, Goodman Gwasira, Felix Henselowsky, Emma Imalwa, Martin Kehl, Janet Rethemeyer, Astrid Röpke, Judith Sealy, Ingrid Stengel, Madelon Tusenius   +14 more
openalex   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

Middle Stone Age marine resource exploitation at Ysterfontein 1 rockshelter, South Africa. [PDF]

Proc Natl Acad Sci U S A, 2021
Klein RG.
europepmc   +1 more source